Evidence map›Paper›PMID 40391786›Full record

ArticleCancer communications (London, England)2025

Targeted reactivation of the novel tumor suppressor DAPK1, an upstream regulator of p53, in high-grade serous ovarian cancer by mRNA liposomes reduces viability and enhances drug sensitivity in preclinical models.

Monika Raab, Balázs Győrffy, Samuel Peña-Llopis, Daniela Fietz, Monika Kressin, Margareta Kolaric, Matthias Ebert, Khayal Gasimli, Sven Becker, Mourad Sanhaji and 1 more

Abstract read
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In one paragraph

Article in Cancer communications (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Monika RaabDepartment of Gynecology, Medical School, Goethe University, Frankfurt (Main), Germany.
Balázs GyőrffyDepartment of Bioinformatics and Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Samuel Peña-LlopisTranslational Genomics, Department of Ophthalmology, University Hospital Essen, Essen, Germany.ORCID https://orcid.org/0000-0003-3847-1353
Daniela FietzInstitute for Veterinary Anatomy, Histology and Embryology, Giessen, Germany.
Monika KressinInstitute for Veterinary Anatomy, Histology and Embryology, Giessen, Germany.
Margareta KolaricGeorg-Speyer-Haus, Goethe University, Frankfurt, Germany.
Matthias EbertGeorg-Speyer-Haus, Goethe University, Frankfurt, Germany.
Khayal GasimliDepartment of Gynecology, Medical School, Goethe University, Frankfurt (Main), Germany.
Sven BeckerDepartment of Gynecology, Medical School, Goethe University, Frankfurt (Main), Germany.
Mourad SanhajiDepartment of Gynecology, Medical School, Goethe University, Frankfurt (Main), Germany.
Klaus StrebhardtDepartment of Gynecology, Medical School, Goethe University, Frankfurt (Main), Germany.ORCID https://orcid.org/0000-0001-8202-0694

Funding

Deutsche Krebshilfe 70116875
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40391786
PMCPMC12365538

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.