Evidence map›Paper›PMID 40391753›Full record

ReviewCancer medicine2025

Lipid Metabolism in Gastrointestinal Malignancies: Exploring Dysregulation, Biomarkers, and Treatment Strategies.

Yan An, Huihui Song, Hongyan Qiu, Jun Jiang, Junfeng Shi

Abstract readReview
In one paragraph

Review in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yan AnDepartment of Anesthesiology, Affiliated Hospital of Shandong Second Medical University, Weifang, China.
Huihui SongObstetrical Medicine Center, Weifang People's Hospital, Shandong Second Medical University, Weifang, China.
Hongyan QiuDepartment of Endocrinology and Metabolism, School of Clinical Medicine, Affiliated Hospital of Shandong Second Medical University, Shandong Second Medical University, Weifang, China.
Jun JiangDepartment of Anesthesiology, Affiliated Hospital of Shandong Second Medical University, Weifang, China.ORCID https://orcid.org/0000-0003-3091-9512
Junfeng ShiDepartment of Endocrinology and Metabolism, School of Clinical Medicine, Affiliated Hospital of Shandong Second Medical University, Shandong Second Medical University, Weifang, China.ORCID https://orcid.org/0000-0003-3950-4073

Funding

Natural Science Foundation of Shandong Province of China ZR2021QD132Shandong Traditional Chinese Medicine Science and Technology Project Q2023147Weifang science and Technology Development Program 2023YX057
6 · The paper itself

Abstract

backgroundGastrointestinal malignancies are a major public health concern worldwide, characterized by high incidence and mortality rates. Despite continuous advancements in existing treatment methods, overall survival rates remain low. Lipid metabolism plays a crucial role in the occurrence, progression, and treatment of gastrointestinal malignancies. Its involvement in the metabolic reprogramming of tumor cells, regulation of the tumor microenvironment, and drug response has become a research hotspot. MATERIALS &

methodsThis review summarizes current research related to lipid metabolism mechanisms, biomarkers, and therapies in GI cancers, with emphasis on its interaction with the tumor microenvironment.

Indexed as

Biomarkers, TumorGastrointestinal NeoplasmsLipid MetabolismHumansTumor MicroenvironmentBiomarkers, Tumorbiomarkersgastrointestinal malignancieslipid metabolismlipid‐targeted therapyTME

Identifiers

PMID40391753
PMCPMC12090204

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.