Evidence map›Paper›PMID 40391669›Full record

ArticleAngewandte Chemie (International ed. in English)2025

Rapid Access to an Enantioenriched Spiro Bisindole Directly from Indole and Acetone.

Jing-Yi Wang, Jie Lin, Chaoshen Zhang, Jianwei Sun

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
  6. Rapid Access to an Enantioenriched Spiro Bisindole Directly from Indole and Acetone.Angewandte Chemie (International ed. in English) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jing-Yi WangDepartment of Chemistry and the Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration & Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, 999077, Hong Kong SAR (China).
Jie LinDepartment of Chemistry and the Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration & Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, 999077, Hong Kong SAR (China).
Chaoshen ZhangDepartment of Chemistry and the Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration & Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, 999077, Hong Kong SAR (China).
Jianwei SunDepartment of Chemistry and the Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration & Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, 999077, Hong Kong SAR (China).ORCID https://orcid.org/0000-0002-2470-1077

Funding

Hong Kong Research Grants Council 16304322Hong Kong Research Grants Council 16309321Hong Kong Research Grants Council 16309722Hong Kong Research Grants Council 16310924Hong Kong Research Grants Council C6012-21GInnovation and Technology Commission ITC-CNERC14SC01National Natural Science Foundation of China 22271242National Natural Science Foundation of China 22471232
6 · The paper itself

Abstract

Disclosed here is a "one-pot self-assembly" strategy for the enantioselective synthesis of a spiro bisindole molecule directly from indole and acetone. This convenient synthesis contrasts drastically to the typical long sequence required for other privileged C

Indexed as

Asymmetric synthesisChiralityEnantioselectivityIndolesSpirocyclic compounds

Identifiers

PMID40391669
PMCPMC12281080

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.