Evidence map›Paper›PMID 40391506›Full record

ArticleJournal of biomedical research2025

Washed microbiota transplantation effectively treats a case of acute severe ulcerative colitis combined with viral myocarditis.

Rujun Ai, Yan Jin, Faming Zhang, Bota Cui, Guozhong Ji

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomedical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rujun AiDepartment of Microbiota Medicine & Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210011, China.
Yan JinWuxi Second People's Hospital, Affiliated Middle School Hospital of Jiangnan University, Wuxi, Jiangsu 214000, China.
Faming ZhangDepartment of Microbiota Medicine & Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210011, China.
Bota CuiDepartment of Microbiota Medicine & Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210011, China.
Guozhong JiDepartment of Microbiota Medicine & Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210011, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral myocarditis is a rare but life-threatening complication in patients with ulcerative colitis. Management of myocarditis is primarily supportive, because there are currently no established targeted therapies. Recent studies have increasingly highlighted the association between the gut microbiota and myocarditis. Here, we report a case of acute severe ulcerative colitis complicated by cytomegalovirus and Epstein-Barr virus co-infections that led to viral myocarditis. The patient experienced rapid remission of both intestinal and cardiac symptoms following washed microbiota transplantation, suggesting this intervention may serve as a potential alternative treatment for these life-threatening conditions.

Indexed as

cytomegalovirusEpstein-Barr virusfecal microbiota transplantmicrobiomeulcerative colitisviral myocarditis

Identifiers

PMID40391506
PMCPMC12329411

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.