Evidence map›Paper›PMID 40391324›Full record

ArticlebioRxiv : the preprint server for biology2025

An enteric neuron-expressed variant ionotropic receptor detects ingested salts to regulate salt stress resistance.

Jihye Yeon, Laurie Chen, Nikhila Krishnan, Sam Bates, Charmi Porwal, Piali Sengupta

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jihye YeonDepartment of Biology, Brandeis University, Waltham, MA 02454.ORCID 0000-0001-9995-1129
Laurie ChenDepartment of Biology, Brandeis University, Waltham, MA 02454.
Nikhila KrishnanDepartment of Biology, Brandeis University, Waltham, MA 02454.
Sam BatesDepartment of Biology, Brandeis University, Waltham, MA 02454.
Charmi PorwalDepartment of Biology, Brandeis University, Waltham, MA 02454.
Piali SenguptaDepartment of Biology, Brandeis University, Waltham, MA 02454.ORCID 0000-0001-7468-0035

Funding

NEUROSCIENCE: FROM CHANNELS TO BEHAVIORT32MH019929 · NIMH · BRANDEIS UNIVERSITY · PI GRIFFITH, LESLIE C · 1994 to 2023
$8.5M
Mechanisms of sensory neuron morphological diversification, signaling, and functional plasticityR35GM122463 · NIGMS · BRANDEIS UNIVERSITY · PI Piali Sengupta · 2017 to 2026
$7.7M
Predoctoral Training in Cross-Disciplinary Molecular and Cellular BiologyT32GM139798 · NIGMS · BRANDEIS UNIVERSITY · PI Paul Garrity, Bruce L Goode · 2021 to 2026
$3.5M
NIGMS NIH HHS R35 GM122463NIGMS NIH HHS T32 GM139798NIMH NIH HHS T32 MH019929
6 · The paper itself

Abstract

The detection of internal chemicals by interoceptive chemosensory pathways is critical for regulating metabolism and physiology. The molecular identities of interoceptors, and the functional consequences of chemosensation by specific interoceptive neurons remain to be fully described. The

Indexed as

acclimationC. elegansenteric neuroninteroceptionionotropic receptorsalt stress

Identifiers

PMID40391324
PMCPMC12087990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.