ArticleFrontiers in psychiatry2025
A multi-centred pilot randomised controlled trial of learning through play plus culturally adapted cognitive behaviour therapy for treating postnatal depression in Nigerian women.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04644081 (Learning Through Play Plus Culturally Adapted Cognitive Behaviour Therapy for Treating Postnatal Depression and Improving Child Wellbeing in Jos Nigeria), which is not on this map. Not yet cited in PubMed.
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Learning Through Play Plus Culturally Adapted Cognitive Behaviour Therapy for Treating Postnatal Depression and Improving Child Wellbeing in Jos Nigeria: A Pilot Randomised Control Trial
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11 authors.
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Abstract
Background: About 13% of women globally experience postnatal depression with adverse implications for the mothers and their children. In Nigeria, there is limited access to evidence-based culturally appropriate care for mothers affected by postnatal depression. Methods: This study was a multi-centre, two-arm, parallel-group, single-blind, individually randomised controlled trial design adopted to test the feasibility, cultural appropriateness and acceptability of Learning Through Play plus Culturally adapted Cognitive Behaviour Therapy (LTP+CaCBT). The LTP+CaCBT is a 12-session (90 minutes each) intervention to treat postnatal depression, and this was compared with the Enhanced Treatment As Usual (ETAU). Sixty-six mother-child pairs across three centres who scored >5 on the Patient Health Questionnaire (PHQ-9) were recruited for the study and randomised to either the LTP+CaCBT experimental or ETAU control groups. Data were collected at various time points (baseline, end of intervention and 3 months post-enrolment) and analysed using appropriate descriptive and inferential statistics. N = 3 focus groups comprising 11 participants each and n = 18 individual interviews were conducted to explore participants' experiences engaging with the intervention. Interviews were transcribed verbatim and analysed using interpretative phenomenological analysis. Result: The LTP+CaCBT group (n=33) recorded a high participants' recruitment, participation and retention rate of 94% across 12 sessions. Satisfaction with intervention (LTP+CaCBT, 97%; ETAU, 34.4%). reduction in postnatal depression was higher in LTP+CaCBT on PHQ-9 Conclusion: The LTP+CaCBT intervention is shown to be acceptable and culturally appropriate whilst indicating potential clinical effectiveness in reducing postnatal depression and anxiety in Nigerian mothers. A fully powered RCT is recommended to evaluate the clinical and cost-effectiveness of LTP+CaCBT, including the child's outcomes compared with ETAU. Clinical trial registration: https://clinicaltrials.gov/study/NCT04644081, identifier NCT04644081.
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