Evidence map›Paper›PMID 40391226›Full record

ArticleFrontiers in immunology2025

Blue light-emitting diode phototherapy presents

Breno Luiz Pimenta, Daniela Pagliara Lage, Camila Simões de Freitas, Danniele Luciana Vale, Karolina Oliveira de Melo Falcão, Saulo Samuel Gonçalves Dias, Raquel Soares Bandeira Câmara, Isabela Amorim Gonçalves Pereira, Ana Luiza Silva, Lauro de Assis Duarte Júnior and 4 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Breno Luiz PimentaPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Daniela Pagliara LagePrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Camila Simões de FreitasPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Danniele Luciana ValePrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Karolina Oliveira de Melo FalcãoDepartamento de Patologia Clínica, Colégio Técnico da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Saulo Samuel Gonçalves DiasDepartamento de Patologia Clínica, Colégio Técnico da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Raquel Soares Bandeira CâmaraPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Isabela Amorim Gonçalves PereiraPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Ana Luiza SilvaPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Lauro de Assis Duarte JúniorLaboratório de Imunobiologia da Inflamação, Departamento de Ciências Biológicas, Instituto de Ciências Exatas e Biológicas (ICEB), Universidade Federal de Ouro Preto, Ouro Preto, Brazil.
Miguel Angel Chavez-FumagalliComputational Biology and Chemistry Research Group, Vicerrectorado de Investigación, Universidad Católica de Santa María, Arequipa, Peru.
Rodrigo Fernando BianchiLaboratório de Polímeros e Propriedades Eletrônicas de Materiais, Instituto de Ciências Exatas e Biológicas (ICEB), Universidade Federal de Ouro Preto, Ouro Preto, Brazil.
Eduardo Antonio Ferraz CoelhoPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
André TalvaniPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of tegumentary leishmaniasis (TL) faces significant challenges, including drug toxicity, high costs, and the emergence of resistant strains. These limitations highlight the urgent need for novel antileishmanial agents and therapeutic strategies. This study evaluated blue light-emitting diode (LED) phototherapy as an alternative approach to inhibit

Indexed as

LeishmaniaLeishmaniasis, CutaneousPhototherapyAmphotericin BAnimalsBlue LightDisease Models, AnimalFemaleMacrophagesMiceMice, Inbred BALB CParasite LoadAmphotericin Bamphotericin Bantileishmanial activityblue LED phototherapyimmune responsetegumentary leishmaniasistreatment

Identifiers

PMID40391226
PMCPMC12086167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.