Evidence map›Paper›PMID 40391172›Full record

ArticleJAC-antimicrobial resistance2025

Ceftobiprole in cystic fibrosis: a case series.

Lisa Nwankwo, Silke Schelenz, Newara Ramadan

Abstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lisa NwankwoPharmacy Department, Royal Brompton and Harefield Hospital, Guy's and St. Thomas' NHS Foundation Trust, London SW3 6NP, UK.ORCID https://orcid.org/0000-0001-9146-2873
Silke SchelenzMicrobiology Department, Kings College Hospital, London SE5 9RS, UK.
Newara RamadanMicrobiology Department, Royal Brompton and Harefield Hospital, Guy's and St. Thomas' NHS Foundation Trust, London SW3 6NP, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the CF transmembrane conductance ( Objectives: To describe the use of ceftobiprole in the treatment of infective exacerbations in CF. Patients and methods: Ten patients with CF (age 24-63; six male and four female) were treated with ceftobiprole for infective exacerbations following discussion within the multi-disciplinary team. In most patients, ceftobiprole was given concomitantly with other antibiotics. Results: All patients had positive sputum cultures for Conclusions: Ceftobiprole presents a therapeutic option for susceptible infections in CF patients with limited treatment options. Its broad-spectrum coverage may help to reduce polypharmacy. However, further clinical studies are needed.

Identifiers

PMID40391172
PMCPMC12086531

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.