Evidence map›Paper›PMID 40391107›Full record

SynthesisFrontiers in psychology2025

Effectiveness of preventive interventions on adolescents' depression and suicidal tendency: a systematic review of randomized controlled trials.

Lubna Ghazal, Naixue Cui, Cao Fenglin, Erika Sivarajan Froelicher, Mulugeta Shegaze Shimbrer

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Predicting adolescent depression: an interpretable machine learning model.BMC medical informatics and decision making · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lubna GhazalSchool of Nursing and Rehabilitation, Cheeloo Medical College, Shandong University, Jinan, China.
Naixue CuiSchool of Nursing and Rehabilitation, Cheeloo Medical College, Shandong University, Jinan, China.
Cao FenglinResearch and International Affairs at Cheeloo Medical College, Shandong University, Jinan, China.
Erika Sivarajan FroelicherSchool of Medicine, University of California San Francisco, San Francisco, CA, United States.
Mulugeta Shegaze ShimbrerSchool of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study was conducted to review the effectiveness of preventive mental health interventions for adolescents (aged 11-19 years) in reducing depression and suicidal tendencies. Methods: A systematic search was conducted to identify randomized controlled trials (RCTs) from the databases Results: Out of 1,210 studies, 13 RCTs were incorporated. The interventions yielded varied outcomes, with approximately half of the RCTs demonstrating reductions in depression and suicidal tendencies, comparable to the control group. Post-intervention, the majority of interventions exhibited mild to moderate effect sizes; however, further research is warranted to assess their long-term efficacy. Cognitive-behavioral therapy (CBT)-based psychoeducation interventions served as the primary approach, often implemented in school settings. However, these interventions were primarily delivered by specialists rather than teachers. Parental involvement in treatment emerged as a potential factor that could enhance the effectiveness of preventive interventions. Discussion and conclusion: While numerous interventions in this review showed effects comparable to control groups, the diversity in methodology, intervention types, and outcome measures poses challenges in drawing definitive conclusions. Therefore, future research should prioritize addressing these methodological discrepancies within their respective contexts.

Indexed as

adolescentschildrendepressionpreventionpromotionsuicide

Identifiers

PMID40391107
PMCPMC12087179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.