ReviewClinical ophthalmology (Auckland, N.Z.)2025
Revolutionizing Retinal Therapy: The Role of Nanoparticle Drug Carriers in Managing Vascular Retinal Disorders.
Review in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- MicroRNAs: A Social Network in Diabetic Retinopathy.Biomolecules · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vascular Retinopathy (VR), such as diabetic retinopathy, pose significant challenges to vision and overall health. Traditional treatment methods often face limitations in efficacy and delivery. Vascular retinopathy is a common and potentially blinding group of eye diseases with core pathologic mechanisms involving vascular injury, ischemia, exudation, and neovascularization. Clinical management relies heavily on etiologic control (eg, diabetes, hypertension), anti-VEGF therapy, laser therapy, and surgical intervention. Recent advancements in nanotechnology have led to the development of innovative nanoparticle drug carriers, which offer promising solutions for targeted and sustained drug delivery in the retinal environment. This review explores the application of both conventional and novel nanoparticle carriers in treating VR. We discuss various types of nanoparticles, including liposomes, polymeric nanoparticles, and metal-based carriers, highlighting their unique properties, mechanisms of action, and therapeutic benefits. Finally, we provide insights into future perspectives for nanoparticle-based therapies in retinal disorders, emphasizing the potential for improved patient outcomes and the need for further research to optimize these advanced drug delivery systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.