ArticleERJ open research2025
A comprehensive evaluation of murine and human
Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Virulence determinants of Fusarium oxysporum for clinical infections.PLoS pathogens · 2026Article
- Readiness of theFrontiers in toxicology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Alveolar macrophages (AMs) serve as the frontline defence in the lungs; however, comprehensive cell culture models for their study remain limited. Freshly isolated AMs are hindered by restricted quantities (mice) or challenges in accessing donors (humans). Recently, murine fetal liver-derived macrophages cultured with granulocyte-macrophages colony-stimulating factor were proposed as AMs-like macrophage (called MPI). Furthermore, recent technical progress improved the culture and expansion of primary murine AMs. Methods: We examined three distinct Results: We observed that: 1) isolated AMs from mice and humans can be cultured for several days (human) or months (mice) with minor loss of AM-specific surface markers expression over time; 2) MPI is a self-replicative macrophage model that is easy to culture but lacks the typical AM surface expression marker ( Conclusion: Our study provides a comprehensive comparison of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.