ArticleJournal of obstetrics and gynaecology of India2025
Leydig Cell Tumour of Ovary in a Postmenopausal Woman: A Rare Occurrence.
Article in Journal of obstetrics and gynaecology of India, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leydig cell tumours originate from ovarian sex cord stroma and compromise less than 0.1% of all ovarian tumours. Their unregulated testosterone secretion results in hyperandrogenism and virilization. A 62year old postmenopausal Para 2 patient presented at Father Muller medical college hospital Mangalore with rapidly progressive hirsutism and alopecia since 1 year. Physical examination revealed high grade hirsutism and Internal examination revealed bulky uterus and a 4 x 4 cm right adnexal mass. Pelvic ultrasonography revealed 3.3 x 3.5centimetres right adnexal solid lesion, which was confirmed on MRI. Blood investigations revealed high serum testosterone with normal DHEA-S and serum cortisol. Low dose dexamethasone suppression test confirmed ovary to be the source of elevated testosterone. She underwent stagging laparotomy with frozen section. Frozen section revealed features of benign sex cord stromal tumours. Final histopathological examination revealed pure Leydig cell tumour with Reinke crystals without infiltrated blood vessels or nerves. While investigating a case of postmenopausal hyperandrogenism, ovarian cancers and adrenal cancers should be considered. The final diagnosis is by histopathological evaluation of the tumour which is considered as the gold standard. These postmenopausal virilizing ovarian tumours are most often benign but they require surgery which is the main stay of treatment to control the symptoms. In those patients who have an advanced disease or have recurrence, it is recommended that adjuvant chemotherapy be given.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.