ArticleJournal of obstetrics and gynaecology of India2025
Estimation of Glycosylated Fibronectin as a Predictor of Hypertensive Disorder and Its Severity in Primigravida: A Prospective Observational Cohort Study.
Article in Journal of obstetrics and gynaecology of India, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose of the Study: Glycosylated fibronectin as a predictor of hypertensive disorder and its severity in primigravida. Materials and Methods: It is a prospective observational cohort study done in 100 primigravida into two groups at 28-38 weeks. Group A consists of 24 patients with risk factors of hypertension but not clinically hypertensive. Group B consists of 76 patients who were already hypertensive. GlyFn levels were determined in maternal serum sample by Lumella test kit, and the ability of GlyFn to assess PE status was analyzed. Results: In Group A, 19 cases were GlyFN positive out of which 14 (73%) developed PE later. In Group B, 100% cases of severe PE showed GlyFN positive ( Conclusion: Our study results demonstrate that test has high sensitivity and PPV for preeclampsia that can be a useful adjunct in risk assessment and prediction of preeclampsia.
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