ArticleJournal of obstetrics and gynaecology of India2025
Analysis of Maternal Near-miss and Mortality with Hematologic Diseases in a Single Quaternary Referral Center in Southern Thailand.
Article in Journal of obstetrics and gynaecology of India, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: To assess the causes and clinical outcomes of maternal near-misses and mortality associated with hematologic diseases. Methods: We retrospectively reviewed the medical records from women who experienced maternal near-misses or mortality attributed to hematological diseases during pregnancy or within 42 days of pregnancy termination, following the World Health Organization criteria, at a single quaternary referral center in Southern Thailand, from 2006 to 2021. Results: A total of 109 cases were analyzed, including five maternal deaths and 104 near-miss cases related to hematologic diseases. The median (min-max) maternal age was 29 (14-43) years, with 57.8% of the women being multiparous. The most common hematologic diseases were immune thrombocytopenia (68.8%), acute leukemia (6.4%), and aplastic anemia (6.4%). Of these, 48.6% were diagnosed before pregnancy and 57.8% exhibited a platelet count < 50 × 10 Conclusion: The primary hematologic diseases causing maternal near-miss and mortality were immune thrombocytopenia, acute leukemia, and aplastic anemia. Acute leukemia was the leading cause of death.
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