ArticleJournal of obstetrics and gynaecology of India2025
Is JAK Inhibitor A Therapeutic Option For Endometriosis?
Article in Journal of obstetrics and gynaecology of India, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Molecular mechanisms in endometriosis: linking JAK/STAT pathway, ferroptosis, and microbial dysbiosis.Molecular biology reports · 2026Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endometriosis is a prevalent gynecological disorder that often leads to infertility and presents a complex challenge in its diagnosis and management. This report describes a case history of a 38-year-old woman suffering from rheumatoid arthritis and primary infertility who became pregnant after the initiation of tofacitinib treatment for rheumatoid arthritis. Her disease activity was well-controlled, and she became pregnant six months after the initiation of tofacitinib. We could not find any earlier reports of pregnancy in humans following tofacitinib treatment for endometriosis-related infertility in the literature. This observation suggests a potential link between the JAK pathway, inflammation associated with endometriosis and fertility. Although promising, cautious exploration of the possibility with large controlled studies are essential to validate these findings and assess the safety and efficacy of JAK inhibitors in endometriosis treatment.
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