Evidence map›Paper›PMID 40390778›Full record

ArticleThe journal of venomous animals and toxins including tropical diseases2025

A comprehensive overview of fish envenomation and venom toxicity in Brazil.

Mônica Lopes-Ferreira, Felipe Justiniano Pinto, Yasmin Stefanie Oliveira Costa, Alessa Aparecida Burgarelli, Louise Lene Gomes Lima, Bibiana da Silva Marques, Carla Simone Seibert, Elineide Eugenio Marques, Patrícia Charvet, Vidal Haddad and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of venomous animals and toxins including tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mônica Lopes-FerreiraImmunoregulation Unit, Laboratory of Applied Toxinology (CAT/CeTICS-FAPESP), Butantan Institute, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-0244-7482
Felipe Justiniano PintoImmunoregulation Unit, Laboratory of Applied Toxinology (CAT/CeTICS-FAPESP), Butantan Institute, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-4207-940X
Yasmin Stefanie Oliveira CostaImmunoregulation Unit, Laboratory of Applied Toxinology (CAT/CeTICS-FAPESP), Butantan Institute, São Paulo, SP, Brazil.ORCID https://orcid.org/0009-0003-3668-5662
Alessa Aparecida BurgarelliImmunoregulation Unit, Laboratory of Applied Toxinology (CAT/CeTICS-FAPESP), Butantan Institute, São Paulo, SP, Brazil.ORCID https://orcid.org/0009-0000-0179-607X
Louise Lene Gomes LimaImmunoregulation Unit, Laboratory of Applied Toxinology (CAT/CeTICS-FAPESP), Butantan Institute, São Paulo, SP, Brazil.ORCID https://orcid.org/0009-0004-7575-420X
Bibiana da Silva MarquesImmunoregulation Unit, Laboratory of Applied Toxinology (CAT/CeTICS-FAPESP), Butantan Institute, São Paulo, SP, Brazil.ORCID https://orcid.org/0009-0007-5657-5857
Carla Simone SeibertGraduate Program in Environmental Sciences, Federal University of Tocantins, Palmas, TO, Brazil.ORCID https://orcid.org/0000-0002-3988-7767
Elineide Eugenio MarquesGraduate Program in Environmental Sciences, Federal University of Tocantins, Palmas, TO, Brazil.ORCID https://orcid.org/0000-0003-0223-6853
Patrícia CharvetGraduate Program in Systematics, Use, and Conservation of Biodiversity, Department of Biology, Center for Sciences, Federal University of Ceará, Fortaleza, CE, Brazil.ORCID https://orcid.org/0000-0002-8801-433X
Vidal HaddadDepartment of Dermatology, Botucatu Medical School (FMB), São Paulo State University (UNESP), Botucatu, SP, Brazil.ORCID https://orcid.org/0000-0001-7214-0422
João Gabriel Dos Santos RosaImmunoregulation Unit, Laboratory of Applied Toxinology (CAT/CeTICS-FAPESP), Butantan Institute, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-1738-2634
Geonildo Rodrigo DisnerImmunoregulation Unit, Laboratory of Applied Toxinology (CAT/CeTICS-FAPESP), Butantan Institute, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-4561-1361
Carla LimaImmunoregulation Unit, Laboratory of Applied Toxinology (CAT/CeTICS-FAPESP), Butantan Institute, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-8161-966X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Brazilian waters are home to various venomous fish species, each with its unique venom composition. Although common, envenomation cases are largely underreported, leading to a lack of public health policies for prevention and treatment. Some of the most clinically relevant fish in Brazil include the stingray Methods: We comprehensively searched reports about accidents involving venomous fish in Brazil and compared the toxic activities of some medically relevant species. Results: From the biochemical and toxicological evaluation, we found that venoms show a hierarchy in the ability to induce local toxic effects in mice, probably related to the venom compound diversity with species-specific toxins. Conclusion: Knowledge of fish venom biochemical and toxicological activities is crucial to antivenom therapy development and helps endorse the study of venomous fish and their impact on the public health system.

Indexed as

Biochemical activitiesBrazilian venomous fishComparative studyEnvenomationToxic effects in vivo

Identifiers

PMID40390778
PMCPMC12088643

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.