ArticleJournal of clinical periodontology2025
Differential Response to Non-Surgical Periodontal Therapy Between Intrabony and Suprabony Defects: A Retrospective Analysis.
Article in Journal of clinical periodontology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Timing of Re-Evaluation After Periodontal Therapy: A Randomized Clinical Trial.Journal of periodontal research · 2026Trial
- The Efficacy of Sodium Hypochlorite in Combination with Hyaluronic Acid as an Adjunct to Non-Surgical Periodontal Treatment: A Systematic Review.Antibiotics (Basel, Switzerland) · 2026Review
- Defect morphology dictates success: suprabony lesions outperform intrabony defects in non-surgical periodontal therapy: a 3-month prospective observational study.BMC oral health · 2026Observational
- Differential Response to Non-Surgical Periodontal Therapy Between Intrabony and Suprabony Defects: A Retrospective Analysis.Journal of clinical periodontology · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
aimTo assess the clinical response to Non-Surgical Periodontal Therapy (NSPT) between suprabony and intrabony defects. MATERIALS AND
methodsTotally 200 NSPT patients' records from the King's College London-Oral, Dental and Craniofacial Biobank were included. Periapical radiographs of sites with Periodontal Probing Depth (PPD) > 4 mm were assessed. Changes in periodontal measurements between baseline and three-month re-evaluation were examined and compared across suprabony and intrabony sites. Multilevel analysis was carried out to assess the relative contribution of site-, tooth-, patient- and treatment-related factors on the clinical outcomes.
resultsAlthough intrabony defects showed higher PPD reduction after NSPT compared with suprabony defects, this was a function of initial deeper PPD. In fact, suprabony defects outperformed intrabony defects for 'pocket closure' at every initial PPD threshold and overall were 2.60 times more likely to achieve 'pocket closure'. Defect morphology was one of several factors affecting treatment outcomes. The relative contribution to 'pocket closure' was 64.9% for site-, 26.1% for patient-, 9.0% for tooth- and 1% for treatment-related factors.
conclusionBone defect morphology influences clinical outcome of NSPT, with suprabony defects being twice as likely to achieve pocket closure and resulting in 0.6 mm more PPD reduction compared with intrabony defects.
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Registered trials
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