ArticleActa dermato-venereologica2025
Hidradenitis Suppurativa and Ocular Diseases: Real-world Evidence of 57,972 Patients.
Article in Acta dermato-venereologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Association Between Eosinophilic Esophagitis and Coded Ocular Diagnoses: A Retrospective Cohort Study.Life (Basel, Switzerland) · 2026Article
- Hidradenitis suppurativa: epidemiology, diagnosis, molecular pathogenesis and therapy.Molecular biomedicine · 2026Review
- Atypical facial hidradenitis suppurativa complicated by periorbital cellulitis: Case report and literature review.SAGE open medical case reports · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by recurring dermal abscesses and cutaneous fistulas of intertriginous skin regions, significantly impacting patients' quality of life. While HS has been associated with various comorbidities such as metabolic and chronic inflammatory diseases, many systemic effects of this systemic disease remain to be investigated. In this study, 2 cohorts of patients with and without HS were created - matched for sex, age, and nicotine dependence - each comprising 28,986 patients, using the real-world database TriNetX, to investigate the association of ocular diseases and HS. Not only an increased risk of disorders of refraction and accommodation in HS patients (OR 3.466; 95% CI 3.100, 3.876), but also a higher risk of ocular diseases, including disorders of the lacrimal system, was demonstrated when compared with the control cohort (OR 3.523; 95%CI 2.912, 4.263). Although previous studies have suggested an increased risk of ocular comorbidities in HS patients, ocular history is not routinely queried during visits. Here, the need for further exploration of the association of ocular diseases and HS and for incorporating this into clinical practice is emphasized.
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