ArticleJournal of foot and ankle research2025
Outcomes of Diabetic Toe Amputation With Versus Without Metatarsal Head Resection for Single Ray Wet Gangrene: A Preliminary Study.
Article in Journal of foot and ankle research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundDiabetic wet gangrene of the toes is a serious condition that puts at risk the limb and life of patients. Two types of amputation are used when infection is around the metatarsophalangeal joint (MTPJ): complete toe disarticulation and toe amputation including metatarsal head resection. Because very few published papers analyzed the results of toe amputation for wet gangrene, our study aimed to evaluate the outcomes of both techniques.
methodsThis is a retrospective comparative study of highly selective patients admitted for a single toe/ray diabetic wet gangrene that were treated with toe amputation through MTPJ (TA-MTPJ) versus toe amputation with resection of the metatarsal head (TA-MHR). Three primary outcomes were set for analysis: healing rate and the frequencies of infection recurrence and additional surgeries, including reamputations.
resultsThe sample included 31 cases: 12 cases (39%) with TA-MTPJ and 19 cases (61%) with TA-MHR. Outcomes of TA-MTPJ versus TA-MHR were as follows: (a) healing frequency 66.7% versus 58% (p = 0.6), (b) infection recurrence 50% versus 52.6% (p = 0.8), (c) osteomyelitis 41.6% versus 42.1% (p = 0.8), and (d) reamputation 33.3% versus 47.3% (p = 0.4).
conclusionsThis study showed high complications after toe amputation for diabetic digital wet gangrene, with a trend for higher frequency of complications after TA-MHR compared to TA-MTPJ. For any type of amputation required for toe wet gangrene, it is likely that a more proximal level of index amputation is required.
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