Evidence map›Paper›PMID 40390146›Full record

ArticleTropical medicine and health2025

Mental health and COVID-19 vaccine hesitancy among health-related university students: a cross-sectional multi-center study.

Thanawat Khongyot, Amy Takyi, Dympna Siysila Ndzeshang, Karl Gwei Njuwa Fai, Tin Zar Win, Latdavanh Vorlasane, Gibson Omwansa Javes, Satoshi Kaneko, Taeko Moriyasu

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Article in Tropical medicine and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Thanawat KhongyotSchool of Pharmacy, Walailak University, Nakhon Si Thammarat, Thailand.
Amy TakyiHealth Information Officer, Apam, Central Region, Ghana.
Dympna Siysila NdzeshangSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.
Karl Gwei Njuwa FaiEpicentre, Médecins Sans Frontières, Yaoundé, Cameroon.
Tin Zar WinSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.
Latdavanh VorlasaneSavannakhet Provincial Hospital, Savannakhet, Lao PDR.
Gibson Omwansa JavesSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.
Satoshi KanekoInstitute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Taeko MoriyasuOffice for Global Relations, Nagasaki University, 1-14 Bunkyo, Nagasaki, 852-8521, Japan. taeko_moriyasu@nagasaki-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe mental health problems during the coronavirus disease 2019 (COVID-19) pandemic may have influenced their decision to receive the COVID-19 vaccine among health-related university students, with potential differences across countries. This study elucidated the association between mental health and COVID-19 vaccine hesitancy of health-related university students in Thailand, Laos, and Japan. We additionally examined the other factors that might relate to COVID-19 vaccine hesitancy.

methodsThe study conducted an online survey from February 4 to 27, 2021, among undergraduate students enrolled in health-related programs at University of Health Sciences (Lao PDR), Walailak University (Thailand), and Nagasaki University (Japan) using a non-probability convenience sampling method. The data were analyzed using multiple logistic regression to identify associations between mental health and self-reported COVID-19 vaccine hesitancy and other potential factors.

resultsThis study analyzed data from 841 students. Japanese students attended hybrid classes (82.45%), while those in Laos and Thailand had entirely online courses. All mental health assessment scores (depression, anxiety, and stress) were higher in Thailand and Laos compared to Japan. Students with very high-stress scores had the highest odds of vaccine hesitancy (aOR 2.67, 95% CI 1.45-4.93). Fear of COVID-19 increased hesitancy, while unbelief in vaccine protection significantly increased it (aOR 2.59, 95% CI 1.86-3.59). Females displayed about two times greater hesitancy (adjusted odds ratio, aOR 2.43, 95% CI 1.68-3.51), which correlated with higher mental health scores.

conclusionsWe highlighted a significant association between mental health and self-report COVID-19 vaccine hesitancy. Interventions, including tailored support, awareness campaigns, and psychological services, can foster trust and vaccine uptake.

Indexed as

Coronavirus diseaseCOVID-19 vaccineMental healthUniversity studentVaccine hesitancy

Identifiers

PMID40390146
PMCPMC12087161

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.