Evidence map›Paper›PMID 40390073›Full record

ReviewRespiratory research2025

Diagnosis of early idiopathic pulmonary fibrosis: current status and future perspective.

Xinya Wang, Xinrui Xia, Yihan Hou, Huaizhe Zhang, Wenyang Han, Jianqi Sun, Feng Li

Abstract readReview
In one paragraph

Review in Respiratory research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Artificial intelligence in respiratory medicine: From diagnosis to treatment and future directions.Chinese medical journal pulmonary and critical care medicine · 2026
    Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xinya Wang *Department of Basic Medical Sciences, School of Medicine, Shanghai Jiao Tong University, No.227, South Chongqing Road, Huangpu, Shanghai, 200025, P.R. China.
Xinrui Xia *Department of Basic Medical Sciences, School of Medicine, Shanghai Jiao Tong University, No.227, South Chongqing Road, Huangpu, Shanghai, 200025, P.R. China.
Yihan HouDepartment of Basic Medical Sciences, School of Medicine, Shanghai Jiao Tong University, No.227, South Chongqing Road, Huangpu, Shanghai, 200025, P.R. China.
Huaizhe ZhangSchool of Biomedical Engineering, School of Shanghai Jiao Tong University, No. 800, Dongchuan Road, Minghang, Shanghai, 200240, P.R. China.
Wenyang HanSchool of Biomedical Engineering, School of Shanghai Jiao Tong University, No. 800, Dongchuan Road, Minghang, Shanghai, 200240, P.R. China.
Jianqi SunSchool of Biomedical Engineering, School of Shanghai Jiao Tong University, No. 800, Dongchuan Road, Minghang, Shanghai, 200240, P.R. China. milesun@sjtu.edu.cn.
Feng LiDepartment of Pulmonary and Critical Care Medicine, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, No.241, West Huaihai Road, Xuhui, Shanghai, 200030, P.R. China. lifeng741@aliyun.com.

Funding

Key Technologies Research and Development Program 2021YFC2500700Shanghai Chest Hospital 2024IIT-M002Shanghai Municipal Health Commission 20244Z0019Student Innovation Training Program of Shanghai Jiao Tong University School of Medicine 19250322
6 · The paper itself

Abstract

The standard approach to diagnosing idiopathic pulmonary fibrosis (IPF) includes identifying the usual interstitial pneumonia (UIP) pattern via high resolution computed tomography (HRCT) or lung biopsy and excluding known causes of interstitial lung disease (ILD). However, limitations of manual interpretation of lung imaging, along with other reasons such as lack of relevant knowledge and non-specific symptoms have hindered the timely diagnosis of IPF. This review proposes the definition of early IPF, emphasizes the diagnostic urgency of early IPF, and highlights current diagnostic strategies and future prospects for early IPF. The integration of artificial intelligence (AI), specifically machine learning (ML) and deep learning (DL), is revolutionizing the diagnostic procedure of early IPF by standardizing and accelerating the interpretation of thoracic images. Innovative bronchoscopic techniques such as transbronchial lung cryobiopsy (TBLC), genomic classifier, and endobronchial optical coherence tomography (EB-OCT) provide less invasive diagnostic alternatives. In addition, chest auscultation, serum biomarkers, and susceptibility genes are pivotal for the indication of early diagnosis. Ongoing research is essential for refining diagnostic methods and treatment strategies for early IPF.

Indexed as

Idiopathic Pulmonary FibrosisLungBronchoscopyEarly DiagnosisForecastingHumansTomography, X-Ray ComputedArtificial intelligenceDiagnosisEarly idiopathic pulmonary fibrosisHigh resolution computed tomography

Identifiers

PMID40390073
PMCPMC12090686

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.