Evidence map›Paper›PMID 40389904›Full record

ArticleBMC musculoskeletal disorders2025

A comparison of arthroscopy combined with continuous irrigation, arthroscopic debridement alone, and open arthrotomy for the treatment of septic arthritis of the native knee.

Jie Xiao, WenTing Wu, Shun Lin, Yun Zheng, KaiFeng Lin, Tao You, QiPing Wu, Feng Shen, Xiu Yang, XueSong Han

Abstract readComparative Study
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Jie XiaoFuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350000, China.
WenTing WuFuzhou South East Eye Hospital, Fuzhou, 350000, China.
Shun LinFuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350000, China.
Yun ZhengFuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350000, China.
KaiFeng LinFuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350000, China.
Tao YouFuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350000, China.
QiPing WuFuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350000, China.
Feng ShenFuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350000, China.
Xiu YangFuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350000, China. yangxiu93yy@163.com.
XueSong HanFuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350000, China. hanber900@163.com.

Funding

900th Hospital of the Joint Logistics Support Force of the PLA 2021JQ06900th Hospital of the Joint Logistics Support Force of the PLA 2021ZD02Fujian Medical University 2023QH1355Natural Science Foundation of Fujian Province 2022Y0065Natural Science Foundation of Fujian Province 2024J011149Startup Fund for Scientific Research, Fujian Medical University 2024QH1406
6 · The paper itself

Abstract

backgroundThe optimal surgical treatment for septic arthritis of the knee remains debatable, with few studies comparing different arthroscopic techniques. Furthermore, no study has simultaneously compared arthroscopy combined with continuous irrigation, arthroscopic debridement alone, and open arthrotomy. This study compared the efficacy and success rates of these three surgical methods and analyzed the risk factors for failure following initial surgery.

methodsData were collected from patients who underwent surgery for native knee septic arthritis at the 900th Hospital of Joint Logistic Support Force in China between 2013 and 2023. A retrospective comparison of demographics, comorbidities, auxiliary examination results, causes, microorganisms, and efficacy outcomes was made among the three surgical groups.

resultsA total of 65 patients (65 knees) were included in the study. All three groups had similar baseline characteristics. Postoperative C-reactive protein levels recovered faster in the continuous irrigation group than in the open group (p < 0.001). Both arthroscopic procedures showed a lower rate of hemoglobin decrease compared with open arthrotomy (p = 0.005 for the continuous irrigation group vs. open group; p = 0.023 for the debridement alone group vs. open group). The initial surgical success rate was higher in the continuous irrigation group (93.3%) than in the open group (65.2%) (p = 0.025). After adjusting for confounding factors through multivariate analysis, this advantage remained, with the risk of initial surgical failure in the open group being 11.31 times that in the continuous irrigation group (odds ratio = 11.31, 95% confidence interval: 1.7-75.24, p = 0.012). No significant differences were observed in postoperative range of motion, pain, or functional scores among the three groups.

conclusionNo significant long-term functional differences were observed among the three surgical methods used to treat septic arthritis of the knee. The continuous irrigation group had an advantage in the early postoperative normalization of CRP levels and a higher initial surgical success rate than the open group. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Arthritis, InfectiousArthroscopyDebridementKnee JointTherapeutic IrrigationAdultCombined Modality TherapyC-Reactive ProteinFemaleHumansMaleMiddle AgedOdds RatioPostoperative PeriodRecovery of FunctionRetrospective StudiesC-Reactive ProteinArthroscopyArthrotomyContinuous irrigationKneeNativeSeptic arthritis

Identifiers

PMID40389904
PMCPMC12087149

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.