Evidence map›Paper›PMID 40389796›Full record

ArticleInternational journal of computer assisted radiology and surgery2025

AI-assisted mesh generation for subject-specific modeling of facial soft tissues.

Nathan Lampen, Xuanang Xu, Daeseung Kim, Tianshu Kuang, Jungwook Lee, Hannah H Deng, Jaime Gateno, Pingkun Yan

Abstract read
In one paragraph

Article in International journal of computer assisted radiology and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Nathan LampenDepartment of Biomedical Engineering and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Xuanang XuDepartment of Biomedical Engineering and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Daeseung KimDepartment of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, TX, 77030, USA.
Tianshu KuangDepartment of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, TX, 77030, USA.
Jungwook LeeDepartment of Biomedical Engineering and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Hannah H DengDepartment of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, TX, 77030, USA.
Jaime GatenoDepartment of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, TX, 77030, USA.
Pingkun YanDepartment of Biomedical Engineering and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA. yanp2@rpi.edu.ORCID http://orcid.org/0000-0002-9779-2141

Funding

Outcome-Driven Approach to Minimize the Risks of Facial Distortion Following CMF SurgeryR01DE021863 · NIDCR · METHODIST HOSPITAL RESEARCH INSTITUTE · PI GATENO, JAIME · 2013 to 2025
$5.1M
Learning-Based Approach for Personalized Craniomaxillofacial Surgical PlanningR01DE027251 · NIDCR · METHODIST HOSPITAL RESEARCH INSTITUTE · PI GATENO, JAIME · 2017 to 2021
$2.9M
NIDCR NIH HHS R01 DE021863NIDCR NIH HHS R01DE021863NIDCR NIH HHS R01 DE027251NIDCR NIH HHS R01DE027251
6 · The paper itself

Abstract

purposeSimulation of reconstructive and cosmetic facial surgeries, such as orthognathic surgery, requires precise, patient-specific soft tissue meshes for outcome prediction. Conventional meshing methods rely on labor-intensive processes, including manual landmark digitization and mesh editing, and often lack point correspondence among subjects. These limitations reduce their efficiency, scalability, and utility in fast-paced clinical environments, highlighting the need for innovative and streamlined meshing techniques.

methodsThis study presents a novel AI-assisted mesh generation (AAMG) approach using Google MediaPipe for real-time facial landmark detection to automate the creation of volumetric meshes of facial soft tissues. By leveraging these landmarks as reference points, the AAMG method generates detailed meshes that accurately reflect individual facial anatomy without manual intervention. To evaluate performance, we compared our automated method with a clinically validated, expert-guided mesh generation (EGMG) method that relies on manual landmark digitization and mesh editing. Both methods were tested on a dataset of 29 subjects who had undergone orthognathic surgery.

resultsThe AAMG method demonstrated high-quality metrics, with a mean Jacobian ratio of 0.83, skewness of 0.25, and an aspect ratio of 2.15, comparable to the EGMG method. Additionally, Chamfer distance analysis showed no significant differences affecting simulation performance between the two methods.

conclusionThe proposed AI-assisted mesh generation method significantly reduces mesh generation time from several hours to under a minute, while maintaining comparable mesh quality and accuracy to a clinically validated, expert-guided mesh generation method. Our method ensures consistent subject-specific meshing by leveraging real-time landmark detection and automated interpolation, improving workflow efficiency for surgical planning.

Indexed as

FaceOrthognathic Surgical ProceduresPatient-Specific ModelingSurgical MeshAdultAnatomic LandmarksFemaleHumansImaging, Three-DimensionalMaleBiomechanicsFinite ElementMeshingSoft TissueSurgical PlanningSurgical Simulation

Identifiers

PMID40389796
PMCPMC12278478

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.