ArticleProstate cancer and prostatic diseases2026
Perioperative outcomes of HoLEP, ThuLEP, and TURP in patients with prostate cancer: results from the GRAND study.
Article in Prostate cancer and prostatic diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- A randomized controlled trial comparing en-bloc vs lobe-by-lobe HoLEP: surgical efficiency and early continence outcomes.Prostate cancer and prostatic diseases · 2026Trial
- Perioperative outcomes and prevalence of urethral strictures during surgery for benign prostatic hyperplasia: results from the GRAND study.World journal of urology · 2026Article
- Aquablation for LUTS due to BPH in men with localized prostate cancer.The Canadian journal of urology · 2026Article
- Hospital caseload thresholds for improved perioperative outcomes during transurethral resection or enucleation of the prostate: results from the GRAND study.World journal of urology · 2026Article
- Treatment Regret in Patients Undergoing Minimally Invasive Treatments for Benign Prostatic Hyperplasia.Journal of clinical medicine · 2026Article
- Peri-operative outcomes of open, laparoscopic and robotic simple prostatectomy.BJU international · 2025Article
- Comparison of Perioperative Outcomes for Prostate Artery Embolization Versus Transurethral Resection of the Prostate and Laser Enucleation for Benign Prostatic Hyperplasia: Results from the GRAND Study.Journal of clinical medicine · 2025Article
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9 authors.
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Abstract
backgroundLimited data exist on the role of holmium laser enucleation of the prostate (HoLEP), thulium laser enucleation of the prostate (ThuLEP), and transurethral resection of the prostate (TURP) in patients with prostate cancer (PCa). We aimed to analyze their perioperative outcomes and trends. MATERIALS AND
methodsThe German Nationwide Inpatient Data (GRAND) registry was used to identify male patients diagnosed with PCa who underwent HoLEP, ThuLEP, or TURP between 2005 and 2022. Multivariable regression analyses were performed to compare perioperative morbidity and mortality.
resultsA total of 221,768 procedures in patients with PCa were performed: 8160 HoLEP, 2285 ThuLEP, and 211,323 TURP. Although TURP remains the predominant technique, the use of HoLEP and ThuLEP has increased significantly in recent years, representing 17% of all cases by 2022. Perioperative outcomes were worse for TURP, with higher transfusion (8.8%) and ICU admission rates (1.7%) compared to HoLEP and ThuLEP (both 2.5% and ≤1.2%, respectively). Postoperative urinary retention and incontinence rates were also lower for laser enucleation techniques than TURP. In patients with PCa undergoing TURP, perioperative outcomes were worse compared to those without PCa, while outcomes for HoLEP and ThuLEP were comparable regardless of PCa status.
conclusionHoLEP and ThuLEP offer improved perioperative outcomes compared to TURP in patients with PCa.
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