ArticleDiscover oncology2025
Current trends and landscape of drug resistance in renal cell carcinoma: a bibliometric analysis.
Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Breakthroughs in malignancy therapy: New advances and emerging trends in renal cell carcinoma.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
introductionRenal cell carcinoma (RCC) is a common type of kidney cancer, and the prognosis for patients with advanced-stage disease remains poor. One major obstacle is the development of drug resistance, which severely limits the effectiveness of therapeutic interventions. This bibliometric study aims to provide a comprehensive overview of current research trends on drug resistance in RCC.
methodsThis study examines publications on drug resistance in RCC from 2000 to 2023, sourced from the Web of Science Core Collection (WoSCC). Detailed analyses were conducted to identify research hotspots, academic collaborations, and emerging trends. CiteSpace, SCImago Graphica, and VOSviewer were utilized to conduct these analyses comprehensively.
resultsThis study analyzed a total of 2,804 publications from the WoSCC database. The number of annual publications showed a consistent upward trend, with an average annual growth rate of 8.12%. The United States had the highest number of publications, followed by China and Japan. The most productive institutions were the University of Texas System, Harvard University, and the National Institutes of Health (NIH). Alfred H. Schinkel emerged as the most prolific author, also having the highest H-index. The three most frequent research categories were oncology, pharmacology and pharmacy, and biochemistry and molecular biology. The evolution of research topics was assessed in 5-year intervals, revealing that recent themes such as ferroptosis and immunotherapy have gained increasing attention. Keyword analysis indicated a shift in research focus toward cell lipid metabolism, androgen receptor and specific molecular signatures.
conclusionThis study offers the first comprehensive bibliometric analysis specifically focused on drug resistance in RCC. It identifies current research trends, highlights emerging hotspots, and provides insights into key contributors and ongoing challenges in the field. Our study provides a theoretical reference and guidance to guide future research efforts to address drug resistance in RCC more effectively.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.