Two-dimensional dynamic multileaf collimator (2DDMLC) technique for improved treatment quality in intensity modulated radiation therapy.

Hyojun Park, Chul Hee Min, So-Yeon Park, Jung-In Kim

Abstract read

In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hyojun ParkDepartment of Radiation Oncology, Seoul National University Hospital, Seoul, 03080, Korea.

Chul Hee MinDepartment of Radiation Convergence Engineering, Yonsei University, Wonju, 26493, Korea.

So-Yeon ParkInstitute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, 03082, Korea.

Jung-In KimDepartment of Radiation Oncology, Seoul National University Hospital, Seoul, 03080, Korea. madangin@outlook.com.

Funding

Korea Hydro and Nuclear Power 2023-Tech-11

6 · The paper itself

Abstract

This study aims to evaluate feasibility of the two-dimensional dynamic MLC (2DDMLC) technique through analytical and experimental investigations, focusing on its potential to improve intensity-modulated radiation therapy (IMRT). The leaf motion calculator (LMC), which calculates the leaf motion of the MLC during the treatment, was developed to obtain the MLC sequence including the bank's movement and anticipate the actual fluence delivery. The effect of the y-axis MLC motion was evaluated by calculating the actual fluence distributions from the optimal fluence maps. The actual fluence maps were compared to those of the conventional MLC. The conformity index (CI) and average difference from the optimal fluence map were calculated. Subsequently, prototype of the 2DDMLC was manufactured by using the Varian Millennium 120

Indexed as

Radiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedHumansRadiotherapy DosageField optimizationIntensity modulated radiotherapyNormal tissue sparingTwo-dimensional dynamic multileaf collimator

Identifiers

PMID40389498

DOI10.1038/s41598-025-01002-5

PMCPMC12089435

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.