ArticleScientific reports2025
Optic nerve sheath diameter measurement in healthy South Iranian adults from a cross-sectional ultrasonographic study.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The measurement of optic nerve sheath diameter (ONSD) is a rapid, safe, and non-invasive method for assessing increased intracranial pressure (ICP). This study aimed to determine the mean ONSD in a healthy Iranian adult population and its correlation with demographic and anthropometric factors. Given that normal ONSD values can vary based on sex, age, ethnicity, and ultrasound techniques, establishing a local reference can enhance clinical assessment. In this cross-sectional study, 100 healthy Iranian adults (mean age 38.7 ± 9.8 years; 60 females) underwent ultrasonographic examination of the left optic nerve sheath. ONSD was measured 3 mm behind the globe in two planes, and the average of these measurements was calculated. The mean axial length (AL) was 23.53 mm (SD ± 0.94), and the mean ONSD was noted at 6.3 mm (SD ± 0.42). Statistical analysis did not reveal significant correlations between ONSD and various demographic or anthropometric factors (P:0.236). This study contributes to the literature by providing local reference values for ONSD in a healthy Iranian adult population, establishing an upper limit of 6.3 mm, and highlighting the consistency of these values with international norms, thereby improving the assessment of ICP in diverse populations.
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