ArticleScientific reports2025
Association of systolic blood pressure time in target range with carotid atherosclerotic plaque and carotid intima-media thickness in hypertensive patients.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Diagnostic value of miR-148b-3p in left ventricular hypertrophy patients with hypertension.BMC cardiovascular disorders · 2026Article
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Authors and funding
8 authors.
Funding
Abstract
To examine the associations between the systolic blood pressure (SBP) time in target range (TTR) and carotid atherosclerosis indicators: carotid intima-media thickness (cIMT) and carotid atherosclerotic plaques (CAPs). We conducted a cross-sectional analysis of 7738 hypertensive participants from the Kailuan study who completed a health examination and carotid ultrasonography. TTR was estimated using linear interpolation method, with SBP falling within 120-140 mmHg. Participants were categorized into four groups according to quartiles of SBP-TTR. Logistic and multivariate linear regression were used to study the associations between SBP-TTR and cIMT/CAPs. Compared with the SBP-TTR < 25% group, cIMT gradually decreased in the other three groups and the cIMT decreased by 0.018 mm for every standard deviation increase in SBP-TTR. Additionally, compared to the SBP-TTR < 25% group, the incidence rates of CAPs were lower in the other three groups. Each one standard deviation increase in SBP-TTR was associated with a 10.6% decrease in the risk of CAPs (0.894 [95% CI 0.814 to 0.982]). Those associations were found independent of conventional risk factors. Our study indicates a negative correlation between SBP-TTR and carotid atherosclerosis among hypertensive individuals. Stabilizing blood pressure within normal ranges could reduce cardiovascular risks in hypertensive patients.
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