Evidence map›Paper›PMID 40389402›Full record

ArticleBlood cancer journal2025

Genomic and transcriptomic determinants of clinical outcomes in patients with AML and DNMT3A mutations.

Sao-Chih Ni, Chi-Yuan Yao, Xavier Cheng-Hong Tsai, Min-Yen Lo, Chien-Yuan Chen, Wan-Hsuan Lee, Chien-Chin Lin, Yuan-Yeh Kuo, Yen-Ling Peng, Mei-Hsuan Tseng and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood cancer journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Sao-Chih NiDepartment of Hematological Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.ORCID http://orcid.org/0000-0001-6337-1448
Chi-Yuan YaoDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.ORCID http://orcid.org/0000-0001-5052-9445
Xavier Cheng-Hong TsaiDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Min-Yen LoGraduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chien-Yuan ChenDepartment of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsin-Chu, Taiwan.
Wan-Hsuan LeeGraduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chien-Chin LinDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.ORCID http://orcid.org/0000-0001-7160-2285
Yuan-Yeh KuoTai-Chen Cell Therapy Center, National Taiwan University, Taipei, Taiwan.ORCID http://orcid.org/0000-0002-6090-9000
Yen-Ling PengDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Mei-Hsuan TsengTai-Chen Cell Therapy Center, National Taiwan University, Taipei, Taiwan.
Yu-Sin WuDepartment of Nursing, National Taiwan University Hospital, Taipei, Taiwan.
Ming-Chih LiuDepartment of Pathology, National Taiwan University Hospital, Taipei, Taiwan.
Liang-In LinDepartment of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.ORCID http://orcid.org/0000-0002-3561-1093
Ming-Kai ChuangDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Bor-Sheng KoDepartment of Hematological Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.ORCID http://orcid.org/0000-0002-7965-7579
Ming YaoDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Jih-Luh TangDepartment of Hematological Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.ORCID http://orcid.org/0000-0003-4021-3281
Feng-Ming TienDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. b92401007@ntu.edu.tw.ORCID http://orcid.org/0000-0003-4513-2472
Wen-Chien ChouDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.ORCID http://orcid.org/0000-0003-2967-698X
Hsin-An HouDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Hwei-Fang TienDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.ORCID http://orcid.org/0000-0002-1384-5593

Funding

Ministry of Health and Welfare (Ministry of Health and Welfare, Taiwan) MOHW 107-TDU-B-211-114009 and 111-TDU-B-221-114001
6 · The paper itself

Abstract

Acute myeloid leukemia (AML) and DNMT3A mutations (DNMT3A

Indexed as

DNA (Cytosine-5-)-MethyltransferasesLeukemia, Myeloid, AcuteMutationTranscriptomeAdolescentAdultAgedAged, 80 and overDNA Methyltransferase 3AFemalefms-Like Tyrosine Kinase 3GenomicsHumansMaleMiddle AgedNucleophosminDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNMT3A protein, humanFLT3 protein, humanfms-Like Tyrosine Kinase 3NPM1 protein, humanNucleophosmin

Identifiers

PMID40389402
PMCPMC12089408

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.