ArticleProceedings of the National Academy of Sciences of the United States of America2025
A tethering mechanism underlies Pin1-catalyzed proline
Christopher C Williams, Jonathan Chuck, Paola Munoz-Tello, Douglas J Kojetin
Abstract read
In one paragraphArticle in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
4 authors.
Christopher C WilliamsSkaggs Graduate School of Chemical and Biological Sciences, Scripps Research, Jupiter, FL 33458.
Jonathan ChuckSkaggs Graduate School of Chemical and Biological Sciences, Scripps Research, Jupiter, FL 33458.
Paola Munoz-TelloDepartment of Biochemistry, Vanderbilt University, Nashville, TN 37232.
Douglas J KojetinDepartment of Integrative Structural and Computational Biology, Scripps Research, and The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, University of Florida, Jupiter, FL 33458.ORCID 0000-0001-8058-6168 Funding
Structural Biology of Multi-Domain Proteins and Multi-Protein Machinery in DNA Replication and RepairR35GM118089 · NIGMS · VANDERBILT UNIVERSITY · PI WALTER J. CHAZIN · 2016 to 2026
$4.9MAcquisition of an 800 MHz NMRS10OD034276 · OD · VANDERBILT UNIVERSITY · PI STONE, MICHAEL P · 2024 to 2024
$2.0MMechanistic studies of corepressor-mediated PPARγ transcriptional repressionR01DK124870 · NIDDK · VANDERBILT UNIVERSITY · PI KOJETIN, DOUGLAS · 2020 to 2023
$1.9MBruker Avance III HD 600 MHz NMR spectrometerS10OD021550 · OD · SCRIPPS FLORIDA · PI KOJETIN, DOUGLAS · 2017 to 2017
$600kConsole upgrades for biological NMR spectrometersS10RR025677 · NCRR · VANDERBILT UNIVERSITY · PI SANDERS, CHARLES R · 2009 to 2009
$460kMolecular mechanism of PIN1-mediated regulation of the nuclear receptor PPARyF31DK134167 · NIDDK · SCRIPPS RESEARCH INSTITUTE, THE · PI WILLIAMS, CHRISTOPHER CONRAD · 2023 to 2025
$80kHHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DEM) F31DK134167HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DEM) R01DK124870NCRR NIH HHS S10 RR025677NIDDK NIH HHS F31 DK134167NIDDK NIH HHS R01 DK124870NIGMS NIH HHS R35 GM118089NIH HHS S10 OD021550NIH HHS S10 OD034276
6 · The paper itselfAbstract
The prolyl isomerase Pin1 catalyzes the
Indexed as
NIMA-Interacting Peptidylprolyl IsomerasePeptidylprolyl IsomerasePPAR gammaProlineAmino Acid MotifsBinding SitesCatalysisHumansIsomerismMitogen-Activated Protein Kinase 1PhosphorylationProtein BindingProtein DomainsMitogen-Activated Protein Kinase 1NIMA-Interacting Peptidylprolyl IsomerasePeptidylprolyl IsomerasePIN1 protein, humanPPAR gammaProlineNMR spectroscopynuclear receptorproline isomerizationprolyl isomerase enzyme
Identifiers
PMID40388619
PMCPMC12130881
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