Evidence map›Paper›PMID 40388503›Full record

ArticlePLoS computational biology2025

MobsPy: A programming language for biochemical reaction networks.

Fabricio Cravo, Gayathri Prakash, Matthias Függer, Thomas Nowak

Abstract read
In one paragraph

Article in PLoS computational biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fabricio CravoUniversité Paris-Saclay, CNRS, ENS Paris-Saclay, LMF, Gif-sur-Yvette, France.
Gayathri PrakashUniversité Paris-Saclay, CNRS, ENS Paris-Saclay, LMF, Gif-sur-Yvette, France.
Matthias FüggerUniversité Paris-Saclay, CNRS, ENS Paris-Saclay, LMF, Gif-sur-Yvette, France.ORCID 0000-0001-5765-0301
Thomas NowakUniversité Paris-Saclay, CNRS, ENS Paris-Saclay, LMF, Gif-sur-Yvette, France.ORCID 0000-0003-1690-9342

Funding

French National Research Agency
6 · The paper itself

Abstract

Biochemical Reaction Networks (BCRNs) model species and their interactions via reactions. They have been extensively used in chemistry and extended to biological settings by generalizing the reactions' kinetics. However, detailed models of biochemical processes tend to result in complex BCRN models. We present the Meta-species Oriented Biosystem Syntax (MobsPy), a language designed to simplify the modeling process using the concept of meta-species. Meta-species are constructed using a bottom-up approach from base species, which represent elementary, simple characteristics. These characteristics are then combined to create meta-species with all their complex behavior. The combined species have characteristics that are the Cartesian product of the base species' characteristics and feature inheritance of reactions involving the base species. New reactions can involve all the states of a meta-species or only a subset that is selected via a query. In particular, reactions of meta-species can express a state change of one of the reactants. MobsPy is deployed as a Python package. We showcase its modeling capabilities by building concise models for biochemical systems from the literature.

Indexed as

Computational BiologyModels, BiologicalProgramming LanguagesSoftwareAlgorithmsComputer SimulationSystems Biology

Identifiers

PMID40388503
PMCPMC12165391

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.