ArticlePloS one2025
Exploring fertility preservation in AYA cancer survivors: Information needs and post-cancer challenges.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
purposeTo explore the experiences of fertility preservation (FP) and cancer-induced infertility among adolescent and young adult (AYA) cancer survivors.
methodsThis cross-sectional, qualitative study was conducted by a sociologist in collaboration with a multidisciplinary team specializing in oncology and reproductive medicine. The sample included 31 AYA cancer survivors (13-35 years old) in remission for at least one year. Participants were recruited from oncology or reproductive departments and via "snowball" sampling. Semi-structured interviews, lasting 1-3 hours, were conducted.
resultsOf the 31 participants (18 women, 13 men), 12 women and 12 men had undergone FP, while 6 women and 1 man had not. Some were fertile, some infertile, and others were unsure of their fertility status. Six women and 5 men had children post-cancer, while others were planning or not considering parenthood. Thus, the respondents' experiences of fertility were varied, and their analysis led to a number of observations: 1) a lack of attention to infertility risks prior to cancer treatment; 2) fertility preservation not linked to an imminent pregnancy after cancer raises unconsidered difficulties; 3) gaps in information and care beyond the question of fertility.
conclusionsThe study reveals a lack of information and attention to AYA-specific issues regarding fertility and endocrine function after cancer. There is a need for tailored informational resources for AYA survivors.
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