Evidence map›Paper›PMID 40388088›Full record

Observational studyAdvances in therapy2025

Glycaemic and Weight Control in People Aged 65 or Younger Newly Diagnosed with Type 2 Diabetes in Spain: Insights from the PRIORITY-T2D Study.

Emilio Ortega, Jennifer Redondo-Antón, Silvia Díaz-Cerezo, Miriam Rubio-de Santos, Irene Romera

Abstract readObservational Study
In one paragraph

Observational study in Advances in therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emilio OrtegaDiabetes Unit, Department of Endocrinology and Nutrition, Hospital Clínic, C. de Villarroel, 170, L'Eixample, 08036, Barcelona, Spain.ORCID http://orcid.org/0000-0002-2217-8905
Jennifer Redondo-AntónEli Lilly and Company, Av. de la Industria, 30, Alcobendas, 28108, Madrid, Spain.ORCID http://orcid.org/0000-0003-2661-5866
Silvia Díaz-CerezoEli Lilly and Company, Av. de la Industria, 30, Alcobendas, 28108, Madrid, Spain.ORCID http://orcid.org/0000-0001-6351-818X
Miriam Rubio-de SantosEli Lilly and Company, Av. de la Industria, 30, Alcobendas, 28108, Madrid, Spain.ORCID http://orcid.org/0000-0001-7393-6334
Irene RomeraEli Lilly and Company, Av. de la Industria, 30, Alcobendas, 28108, Madrid, Spain. romera_irene@lilly.com.ORCID http://orcid.org/0000-0002-1345-9799

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe objective of this study was to determine the number of people within glycated haemoglobin (HbA1c) targets and achieving weight-loss goals during the first 5 years after type 2 diabetes (T2D) diagnosis and to explore the relationship between early weight loss and glycaemic control in routine care in Spain.

methodsThis was an observational retrospective study using IQVIA's electronic medical record database, including adults aged ≤ 65 years newly diagnosed with T2D. Variables included baseline sociodemographic/clinical characteristics, yearly HbA1c and weight data, and treatment patterns. Descriptive statistics and regression analyses were used.

resultsA total of 8973 people with T2D were included (mean age 53 years; mean baseline HbA1c 7.7%; obesity at diagnosis: 64%). During the first 5 years post-T2D diagnosis, 46-63% of the population did not have HbA1c < 6.5%, and > 60%, and > 80% of subjects did not achieve ≥ 5% and ≥ 10% weight loss, respectively. Early weight loss goal achievement (1st year after diagnosis) and weight loss magnitude were associated with a higher percentage of people with HbA1c < 6.5%.

conclusionsMany individuals with T2D did not have HbA1c < 6.5% in the first 5 years after diagnosis and did not achieve ≥ 5% or ≥ 10% weight loss. Early weight loss after T2D diagnosis was associated with higher likelihood of achieving early glycaemic control.

Indexed as

Diabetes Mellitus, Type 2Glycated HemoglobinGlycemic ControlObesityWeight LossAdultAgedBlood GlucoseFemaleHumansMaleMiddle AgedRetrospective StudiesSpainBlood GlucoseGlycated HemoglobinGlycated haemoglobinHealth outcomesSpainTreatment patternsType 2 diabetesWeight loss

Identifiers

PMID40388088
PMCPMC12182470

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.