Evidence map›Paper›PMID 40388042›Full record

ArticleEuropean radiology experimental2025

MRI-based pseudo-CT sequences as a radiation-free alternative to CT for obstetric pelvimetry: a proof-of-concept study.

Caroline Chabot, Mathilde Haegeman, Eya Chaouch, Dana Dumitriu, Renaud Menten, Patricia Steenhaut, Pierre Bernard, Perrine Triqueneaux, Nicolas Michoux, Frédéric E Lecouvet

Registry-linked trialAbstract read
In one paragraph

Article in European radiology experimental, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05381077 (Evaluation of Whole Body Examination by MRI Integrating the "Zero Time Eco" Sequence), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05381077 naunknown statusnot on this map

Evaluation of Whole Body Examination by MRI Integrating the "Zero Time Eco" Sequence (ZTE, Pseudo-CT) for the Detection of Bone Lesions in Multiple Myeloma: Comparison With Pet / CT and Whole Body Scanner

TypeinterventionalSponsorCliniques universitaires Saint-Luc- Université Catholique de LouvainRan2021 to 2023Enrolled30ConditionsMultiple Myeloma, Bone MetastasesArmsMRI
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Caroline Chabot *Department of Medical Imaging, Institut de Recherche Expérimentale et Clinique (IREC), Institut du Cancer Roi Albert II, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.
Mathilde Haegeman *Department of Medical Imaging, Institut de Recherche Expérimentale et Clinique (IREC), Institut du Cancer Roi Albert II, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.
Eya ChaouchDepartment of Medical Imaging, Institut de Recherche Expérimentale et Clinique (IREC), Institut du Cancer Roi Albert II, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.
Dana DumitriuDepartment of Medical Imaging, Institut de Recherche Expérimentale et Clinique (IREC), Institut du Cancer Roi Albert II, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.
Renaud MentenDepartment of Medical Imaging, Institut de Recherche Expérimentale et Clinique (IREC), Institut du Cancer Roi Albert II, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.
Patricia SteenhautDepartment of Obstetrics, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.
Pierre BernardDepartment of Obstetrics, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.
Perrine TriqueneauxDepartment of Medical Imaging, Institut de Recherche Expérimentale et Clinique (IREC), Institut du Cancer Roi Albert II, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.
Nicolas MichouxDepartment of Medical Imaging, Institut de Recherche Expérimentale et Clinique (IREC), Institut du Cancer Roi Albert II, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.
Frédéric E LecouvetDepartment of Medical Imaging, Institut de Recherche Expérimentale et Clinique (IREC), Institut du Cancer Roi Albert II, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium. frederic.lecouvet@saintluc.uclouvain.be.ORCID http://orcid.org/0000-0003-3568-3254

Funding

Fondation Saint Luc NA
6 · The paper itself

Abstract

backgroundPelvimetry is essential in obstetrics for delivery planning. While computed tomography (CT) is the standard, magnetic resonance imaging (MRI) offers a radiation-free alternative with zero echo time (ZTE) and black bone (BB) sequences providing high bone-to-soft tissue contrast within short scan times. This proof-of-concept study evaluates the reliability of these sequences and the agreement with CT for pelvimetry in a predominantly elderly population.

methodsThis retrospective study included 21 female patients who underwent 3-T whole-body MRI including ZTE and BB sequences and

resultsIntra-reader agreement was good regardless of diameter or reader: all ICC ≥ 0.90, repeatability ranging from ± 0.26 to ± 0.48 cm (CT), ± 0.30 to ± 0.52 cm (BB), and ± 0.29 to ± 0.67 cm (ZTE). The inter-reader agreement was good regardless of sequence: all ICC ≥ 0.88, reproducibility ranging from ± 0.39 to ± 0.42 (OCD), ± 0.26 to ± 0.51 cm (ISD), and ± 0.53 to ± 0.58 cm (MTD). ZTE and BB showed similar agreement with CT: ± 0.57 to ± 0.81 cm when including inter-reader variability; ± 0.34 to ± 0.47 cm for only intra-reader variability.

conclusionZTE and BB sequences provided reliable measurements with good agreement with CT, for obstetric pelvimetry. Further validation in the context of pregnancy is needed. RELEVANCE STATEMENT: MRI-based pseudo-CT sequences are a promising radiation-free alternative to CT for obstetric pelvimetry, offering the prospect of accurate, reliable measurements of pelvic diameters in pregnant women.

trial registrationThe population included female patients with suspected multiple myeloma from a previous prospective oncology trial (ClinicalTrials.gov: NCT05381077). KEY POINTS: This study explores pseudo-CT MRI sequences for radiation-free non-invasive obstetric pelvimetry. Pseudo-CT zero echo time and black bone sequences provide repeatable and reproducible measurements of pelvic diameters. Pseudo-CT MRI sequences show good inter-technique agreement with the reference CT.

Indexed as

Magnetic Resonance ImagingPelvimetryTomography, X-Ray ComputedAdultAgedFemaleFluorodeoxyglucose F18HumansMiddle AgedPositron Emission Tomography Computed TomographyPregnancyProof of Concept StudyReproducibility of ResultsRetrospective StudiesFluorodeoxyglucose F18Magnetic resonance imagingObstetricsPelvimetryReproducibility of resultsTomography (x-ray computed)

Identifiers

PMID40388042
PMCPMC12089014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.