Evidence map›Paper›PMID 40387915›Full record

ArticleNeuroradiology2025

Advancing the diagnosis and management of pudendal nerve entrapment: The role of neurophysiological studies and imaging-guided infiltrations.

Cláudia Fernandes, Vanessa Viegas, Manuel Saavedra, Javier Casado, Ana Sánchez, Clara Velasco, Lidia Cabañes, Cecilia Luque, Alberto Artiles, Luís San José and 1 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cláudia FernandesUrology Department, Hospital de São João, Porto, Portugal. fernandes.claudia.med@gmail.com.
Vanessa ViegasUrology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Manuel SaavedraUrology Department, Hospital Universitario de la Princesa, Madrid, Spain.
Javier CasadoUrology Department, Hospital Universitario de la Princesa, Madrid, Spain.
Ana SánchezUrology Department, Hospital Universitario de la Princesa, Madrid, Spain.
Clara VelascoUrology Department, Hospital Universitario de la Princesa, Madrid, Spain.
Lidia CabañesClinical Neurophysiology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Cecilia LuqueClinical Neurophysiology Department, Hospital Universitario de la Princesa, Madrid, Spain.
Alberto ArtilesUrology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Luís San JoséUrology Department, Hospital Universitario de la Princesa, Madrid, Spain.
Luís Lopez-Fando LavalleUrology Department, Hospital Universitario de la Princesa, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePudendal nerve entrapment (PNE) diagnosis is not standardized. This leads to diagnosis delays, impacting quality of life and therapeutic outcomes. The main goal is to find the role of neurophysiological study (NFS) and Imaging-guided pudendal nerve infiltration (ImPNI) in PNE diagnosis and patient selection for surgery.

methodsA retrospective, multicentric study was conducted. Patients with PNE refractory to conservative treatment were included. Patient data, including NFS results, ImPNI, and surgical outcomes, were evaluated. A visual analogue scale was used to assess intervention response. Test performance metrics for NFS and ImPNI and binary logistic regression were used to determine their predictive value for postoperative improvement.

results88 patients were diagnosed with PNE. All had NFS, and ImPNI was performed in 69 (78.4%), with 60 (68.2%) showing symptom improvement. Among the 40 patients (85%) who underwent pudendal nerve decompression surgery, 75% improved after surgery, and 20% did not. The combination of NFS and ImPNI showed a sensitivity of 79% and a specificity of 85.7%, with a Positive Predictive Value (PPV) of 98% and a Negative Predictive Value (NPV) of 30%. NFS and ImPNI were significant predictors of surgical success with p-values of 0.013 [ 95% CI: -23.6-19.9] and 0.003 [95% CI: -20.6 -18.5], respectively. Primary limitations: retrospective design and the absence of a control group.

conclusionsNFS and ImPNI are essential and highly reliable tools for diagnosing PNE. ImPNI is a valuable predictor of surgical outcomes. These findings enable precise patient selection for surgery, ensuring optimal surgical outcomes.

Indexed as

Nerve Compression SyndromesPudendal NervePudendal NeuralgiaRadiography, InterventionalAdultAgedDecompression, SurgicalFemaleHumansMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityTreatment OutcomeCT-guided infiltrationsNeurophysiological studiesPudendal nerve entrapmentPudendal neuralgiaSurgery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.