Evidence map›Paper›PMID 40387605›Full record

SynthesisWorldviews on evidence-based nursing2025

Effects of Nonpharmacological Interventions on Stress, Anxiety, and Depression of Pregnant Women: A Systematic Review and Network Meta-Analysis.

Filiz Değirmenci, Kadriye Pınar Ambarcioğlu Kisaçam, Duygu Vefikuluçay Yilmaz

Abstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in Worldviews on evidence-based nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Filiz DeğirmenciDepartment of Obstetrics and Gynecology Nursing, Mersin University Faculty of Nursing, Mersin, Türkiye.
Kadriye Pınar Ambarcioğlu KisaçamDepartment of Biostatistics, Mustafa Kemal University Faculty of Veterinary Medicine, Hatay, Türkiye.
Duygu Vefikuluçay YilmazDepartment of Obstetrics and Gynecology Nursing, Mersin University Faculty of Nursing, Mersin, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStress, anxiety, and depression during pregnancy can adversely affect maternal, fetal, and child health. To alleviate these symptoms, nonpharmacological interventions have been increasingly utilized as supportive approaches.

aimTo compare nonpharmacological interventions and determine their effectiveness in reducing stress, anxiety, and depression levels during pregnancy.

methodsThis systematic review adheres to the network meta-analysis extension for the Preferred Reporting Items for Systematic Review and Meta-analysis 2015 statement for design and reporting. The included studies were comprised of quasi-randomized and randomized controlled trials that aimed to assess the effectiveness of nonpharmacological interventions on stress, anxiety, and depression in pregnant women. The methodological quality of the included studies was assessed using the Cochrane Collaboration Risk of Bias Tool. Statistical analysis was conducted using the "mvmeta" package in Stata/SE 15. PubMed, APA PsycNET, Web of Science, The Cochrane Library, and Scopus were searched for randomized controlled trials up to December 2021.

resultsThis star network meta-analysis included 38 trials with 3555 pregnant women and eight nonpharmacological interventions for stress, anxiety, and depression. The findings indicate that spiritual meditation was the most effective intervention in reducing stress, anxiety, and depression during pregnancy. Mindfulness-based stress reduction was identified as another effective intervention specifically for reducing stress. Furthermore, during pregnancy, mindfulness-based cognitive therapy was found to be the second most effective intervention in reducing depression. LINKING EVIDENCE TO ACTION: Our research showed that spiritual meditation might be the most effective intervention for reducing stress, anxiety, and depression in pregnant women. Health professionals could consider recommending spiritual meditation as a complementary therapy to pregnant women to reduce stress, anxiety, and depression.

trial registrationPROSPERO International Prospective Register of Systematic Reviews: CRD42021261089.

Indexed as

AnxietyDepressionPregnant PeopleStress, PsychologicalAdultFemaleHumansPregnancyanxietydepressionmental healthnursingpregnancystress

Identifiers

PMID40387605
PMCPMC12087524

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.