SynthesisCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2025
The Effects of Post-diagnosis Recreational Aerobic Exercise among Breast Cancer Survivors: A Systematic Review/Meta-Analysis.
Synthesis in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Blueprint for adapting the cardiac rehabilitation model for oncology patients with cardiovascular-kidney-metabolic syndrome.American journal of preventive cardiology · 2026Article
- Exploring the feasibility of exercise training during (neo)adjuvant chemotherapy in women with early-stage breast cancer: a pilot study examining immune and metabolic outcomes.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- User Perspectives on a Clinical Decision Tool to Support Individualized Exercise Prescriptions for Breast Cancer Survivors Not Meeting Exercise Guidelines: Cross-Sectional Survey.JMIR formative research · 2026Article
- Healthcare provider perspectives on barriers and facilitators to exercise promotion among breast cancer survivors: Differences across professions.Journal of cancer survivorship : research and practice · 2026Article
- Skeletal muscle as an endocrine and paracrine organ in breast cancer biology: a narrative review.Discover oncology · 2026Review
- Tailored Exercise Strategies and Mortality Among Breast Cancer Survivors.JAMA network open · 2026Article
- Article
- Breast cancer survivors' perspectives on a clinical decision tool to support individualized exercise prescriptions and discussions.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Systems approach to integrative oncology in breast cancer care: service design, delivery and patient experiences from a UK center.Frontiers in oncology · 2026Article
- Development and Validation of a Simulation Model-Based Tool to Support Individualized Physical Activity Discussions and Prescriptions for Breast Cancer Survivors.JCO clinical cancer informatics · 2025Article
- Patient-Reported Observance of a Mediterranean Diet and Physical Activity in Patients Living with Breast Cancer: Implications for Primary Care Providers.Journal of primary care & community healthArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
We aimed to estimate the incremental effects of post-diagnosis recreational aerobic exercise and possible variations in effects on recurrence and mortality to support individualized breast cancer survivorship care plans in clinical settings. Seven databases were searched to identify observational studies that examined the effects of exercise on recurrence, breast cancer-specific mortality, and all-cause mortality (ACM) among female breast cancer survivors. Fully adjusted hazard ratios (HR) and 95% confidence intervals were extracted for comparisons reported in relation to no/minimal exercise (reference). Dose-response relationships between exercise and events were examined using restricted cubic splines. Less than half of participants (44.3%, n = 50,689) met aerobic exercise guidelines for health (≥∼2.5 hours/week). Meeting guidelines was associated with a ∼50% reduction in the HR for ACM, with further reductions up to ∼4.5 hours/week. A ∼25% reduction in the HR for ACM was associated with ∼1 hour/week. The 5-year (unadjusted) ACM rates were 11% for no/minimal exercise, 4% for insufficient exercise, and 3% for meeting exercise guidelines (n = 5 studies). There were limited data for subgroups. Similar patterns were observed for recurrence and breast cancer-specific mortality. Exercise may lower the risk of recurrence and mortality among breast cancer survivors. Though meeting guidelines for health offers the greatest benefits, exercise below guideline-recommended exercise levels is also beneficial.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.