ReviewThe Kaohsiung journal of medical sciences2025
Evaluation of Radiofrequency Ablation Safety and Efficacy in Primary Hyperparathyroidism: A Single-Center Retrospective Study in Taiwan and Literature Review.
Review in The Kaohsiung journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Microwave ablation as a minimally invasive treatment for primary hyperparathyroidism: A case report and literature review.Radiology case reports · 2026Article
- Evaluation of Radiofrequency Ablation Safety and Efficacy in Primary Hyperparathyroidism: A Single-Center Retrospective Study in Taiwan and Literature Review.The Kaohsiung journal of medical sciences · 2025Review
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
Radiofrequency ablation (RFA) is increasingly recognized as a minimally invasive option for primary hyperparathyroidism (PHPT). This study aimed to evaluate the effectiveness and safety of ultrasound (US)-guided RFA for the treatment of PHPT in Taiwan. We conducted a retrospective study of patients with PHPT who underwent RFA at a single medical center between March 2020 and January 2023. Serum biochemical samples, changes in parathyroid nodule volume, symptomatic scores, and complications were analyzed at follow-up after RFA. The volume reduction ratio (VRR) and treatment response at 1 year were evaluated. Among the 31 patients, 93.55% achieved a complete response with a VRR of 97.48% at 12 months post-RFA. Serum calcium and intact parathyroid hormone (iPTH) levels were significantly lower immediately after treatment than at baseline. However, a difference in phosphorus levels was noted 1 week later, and the alkaline phosphatase (ALP) level was significantly decreased after 3 months (p < 0.05). Transient hoarseness occurred in three patients and resolved spontaneously within 6 months. US-guided RFA is effective and safe for treating PHPT, with a satisfactory VRR and treatment response. This approach could be an alternative to surgery for ineligible patients.
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