Evidence map›Paper›PMID 40387402›Full record

ArticleJournal of the American Geriatrics Society2025

Tooth Loss and 12-Year Mortality Risk in 8494 Older Adults From Ireland.

Lewis Winning, Siobhan Scarlett, Mark Ward, Michael Crowe, Rose Anne Kenny, Brian O'Connell

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Tooth Loss and 12-Year Mortality Risk in 8494 Older Adults From Ireland.Journal of the American Geriatrics Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lewis WinningDublin Dental University Hospital, Trinity College Dublin, Dublin, Ireland.ORCID 0000-0002-8783-8089
Siobhan ScarlettThe Irish Longitudinal Study on Ageing (TILDA), Trinity College Dublin, Dublin, Ireland.ORCID 0000-0002-3856-2848
Mark WardThe Irish Longitudinal Study on Ageing (TILDA), Trinity College Dublin, Dublin, Ireland.ORCID 0000-0001-6309-4866
Michael CroweDublin Dental University Hospital, Trinity College Dublin, Dublin, Ireland.ORCID 0000-0003-4761-5945
Rose Anne KennyThe Irish Longitudinal Study on Ageing (TILDA), Trinity College Dublin, Dublin, Ireland.ORCID 0000-0002-9336-8124
Brian O'ConnellDublin Dental University Hospital, Trinity College Dublin, Dublin, Ireland.ORCID 0000-0003-4529-7664

Funding

An Roinn SláinteAtlantic PhilanthropiesIrish Life PLC.
6 · The paper itself

Abstract

objectivesTo investigate whether tooth loss is associated with all-cause and cause-specific mortality in older Irish adults.

methodsA total of 8494 participants from The Irish Longitudinal Study on Ageing (TILDA) were included. Survey data were linked to death registration records, covering individuals who participated in TILDA Wave 1 (2009/2010) and died by 31st January 2022. Cox proportional hazards regressions and competing risk survival analyses were employed to examine the longitudinal relationship between tooth loss and both all-cause and cause-specific mortality.

resultsThe mean age of participants at baseline was 63.2 years (SD 10.2). Among the cohort, 3951 (46.5%) were categorized as "Dentate, no denture," 3041 (35.8%) as "Dentate, with denture(s)," and 1502 (17.7%) as "Edentulous." Over a median follow-up of 12 years, 1430 (16.8%) participants died. After adjusting for confounders, edentulous participants had a significantly higher hazard ratio (HR) for all-cause mortality compared to dentate participants with no dentures (HR = 1.42, 95% CI 1.23-1.65, p < 0.001). For cause-specific mortality, edentulism had the greatest sub-distribution hazard ratio (SHR) with respiratory mortality (SHR = 1.57, 95% CI 1.03-2.41, p = 0.04), followed by cancer mortality (SHR = 1.31, 95% CI 1.01-1.71, p = 0.04). There was a nonsignificant association with cardiovascular mortality (SHR = 1.25, 95% CI 0.96-1.63, p = 0.10).

conclusionsEdentulism was independently associated with all-cause mortality in a cohort of 8494 men and women from Ireland. Edentulism was significantly associated with respiratory and cancer mortality.

Indexed as

Tooth LossAgedAged, 80 and overCause of DeathFemaleHumansIrelandLongitudinal StudiesMaleMiddle AgedNeoplasmsProportional Hazards ModelsRisk Factorsagingall‐cause mortalitydenturesoral healthtooth loss

Identifiers

PMID40387402
PMCPMC12396168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.