Evidence map›Paper›PMID 40387341›Full record

ArticlemSphere2025

Takemasa Takii, Hiroyuki Yamada, Chihiro Motozono, Sho Yamasaki, Jordi B Torrelles, Joanne Turner, Aoi Kimishima, Yukihiro Asami, Naoya Ohara, Shigeaki Hida and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Takemasa TakiiDepartment of Mycobacterium Reference and Research, the Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Kiyose, Tokyo, Japan.ORCID 0000-0002-5005-0941
Hiroyuki YamadaDepartment of Mycobacterium Reference and Research, the Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Kiyose, Tokyo, Japan.
Chihiro MotozonoDepartment of Molecular Immunology, Research Institute for Microbial Diseases, The University of Osaka, Suita, Osaka, Japan.
Sho YamasakiDepartment of Molecular Immunology, Research Institute for Microbial Diseases, The University of Osaka, Suita, Osaka, Japan.
Jordi B TorrellesTexas Biomedical Research Institute and International Center for the Advancement of Research & Education (I•CARE), San Antonio, Texas, USA.ORCID 0000-0001-7702-5941
Joanne TurnerTexas Biomedical Research Institute and International Center for the Advancement of Research & Education (I•CARE), San Antonio, Texas, USA.ORCID 0000-0002-0840-7484
Aoi KimishimaLaboratory of Applied Microbial Chemistry, Ōmura Satoshi Memorial Institute, Kitasato University, Minato, Tokyo, Japan.
Yukihiro AsamiLaboratory of Applied Microbial Chemistry, Ōmura Satoshi Memorial Institute, Kitasato University, Minato, Tokyo, Japan.
Naoya OharaDepartment of Oral Microbiology, Graduate School of Medicine, Density and Pharmaceutical Sciences, Okayama University, Okayama, Okayama, Japan.
Shigeaki HidaDepartment of Hygienic Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan.
Hidetoshi HayashiDepartment of Cell Signaling, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan.
Kikuo OnozakiDepartment of Hygienic Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan.

Funding

Japan Agency for Medical Research and Development JP21fk0108590, JP23fk0108591Japan Society for the Promotion of Science 20K07125, 24K09872
6 · The paper itself

Abstract

We previously reported that live, but not dead, virulent IMPORTANCE: The role of "non-classical immune cells," that is, fibroblasts, epithelial cells, adipocytes, etc., except for the "classical immune cells," that is, macrophages and lymphoid cells, is not well known in the infection of Mtb bacilli. We have previously found that live, but not dead, Mtb bacilli induce cell death in human lung fibroblasts, except in human macrophages and monocytes. The present study reveals that fibroblasts ingest Mtb bacilli the same as macrophages and that

Indexed as

FibroblastsLungMycobacterium tuberculosisPyroptosisCell LineCytokinesHumansInflammasomesCytokinesInflammasomescaspasecytokinefibroblastsMycobacterium tuberculosispyroptosisRNA-Seq

Identifiers

PMID40387341
PMCPMC12188705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.