Evidence map›Paper›PMID 40387287›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

A Programmed DNA Dynamic Assembly-Guided Molecular Amplifier for Authentic Information Decryption.

Ning Yang, Jie Zhou, Fengying Yuan, Yajuan Liu, Jia Zhang, Ying Zhuo, Yu Ouyang, Yaqin Chai, Pu Zhang, Ruo Yuan

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ning YangKey Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Chongqing Engineering Laboratory of Nanomaterials & Sensor Technologies, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P. R. China.ORCID https://orcid.org/0000-0002-4697-800X
Jie ZhouKey Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Chongqing Engineering Laboratory of Nanomaterials & Sensor Technologies, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P. R. China.
Fengying YuanKey Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Chongqing Engineering Laboratory of Nanomaterials & Sensor Technologies, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P. R. China.
Yajuan LiuKey Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Chongqing Engineering Laboratory of Nanomaterials & Sensor Technologies, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P. R. China.
Jia ZhangKey Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Chongqing Engineering Laboratory of Nanomaterials & Sensor Technologies, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P. R. China.
Ying ZhuoKey Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Chongqing Engineering Laboratory of Nanomaterials & Sensor Technologies, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P. R. China.ORCID https://orcid.org/0000-0002-4491-1186
Yu OuyangKey Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Chongqing Engineering Laboratory of Nanomaterials & Sensor Technologies, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P. R. China.ORCID https://orcid.org/0000-0002-2418-281X
Yaqin ChaiKey Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Chongqing Engineering Laboratory of Nanomaterials & Sensor Technologies, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P. R. China.ORCID https://orcid.org/0000-0003-4392-9592
Pu ZhangKey Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Chongqing Engineering Laboratory of Nanomaterials & Sensor Technologies, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P. R. China.ORCID https://orcid.org/0000-0003-4203-0542
Ruo YuanKey Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Chongqing Engineering Laboratory of Nanomaterials & Sensor Technologies, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P. R. China.ORCID https://orcid.org/0000-0003-3664-6236

Funding

Brain-Gain Plan of New Chongqing Young Elite Program CQYC20230A04475Fundamental Research Funds for the Central Universities SWU-KR22017Fundamental Research Funds for the Central Universities SWU-XJLJ202303National Natural Science Foundation of China 22174113National Natural Science Foundation of China 22176153National Natural Science Foundation of China 22204129National Natural Science Foundation of China 22374122Natural Science Foundation of Chongqing Municipality CSTB2022NSCQ-MSX0613
6 · The paper itself

Abstract

Nucleic acid-based cryptographic approaches are an innovative emerging field for information process. However, the poor reproducibility and interference from bioenvironment of the existing decryption led to different binary translation according to the fixed threshold defined by "Sender", which seriously affects the authenticity during message communication. Here, a programmed DNA constitutional dynamic network (CDN)-derived adaptive threshold is shown, which is defined by the difference value of the two groups of the output patterns from CDN. Under external stimuli, the threshold is adaptive to the generated dynamic output patterns, which avoids the contrary binary translation from a slight difference on the output under fixed threshold. Importantly, there are two self-calibrating patterns in each output group and the total concentration of constituents from the CDN system are constant, which greatly eliminates the data error. The CDN system is accompanied by computational simulation, which can predict the output patterns of the system at different states. The CDN is used to control the orthogonal and cascaded nanoparticle-based molecular amplifiers to expand the volume of the transmitting message, as well as allow the accurate and specific sensing of DNA. Various state-of-the-art representation is demonstrated by coding and decoding different types of messages.

Indexed as

Computer SecurityDNADNADNA decryptionDNA nanotechnologyDNA self‐assemblyDNA sensingnanomachine

Identifiers

PMID40387287
PMCPMC12165106

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.