Evidence map›Paper›PMID 40387081›Full record

ArticleChemistry & biodiversity2025

Exploring Chemical Variability in the Essential Oil of Artemisia absinthium L. in Relation to Different Phenological Stages and Geographical Location.

Paola Malaspina, Flavio Polito, Andrea Mainetti, Sana Khedhri, Vincenzo De Feo, Laura Cornara

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Cytotoxic Activity ofInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Low-ThujoneMolecules (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Essential Oils from Pruning Residues ofMolecules (Basel, Switzerland) · 2026
    Article
  8. Article
  9. HarnessingInternational journal of molecular sciences · 2025
    Review
  10. Article
  11. Article
  12. Intraspecific Variability of Wormwood (Molecules (Basel, Switzerland) · 2025
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paola MalaspinaDepartment of Earth, Environment and Life Sciences (DISTAV), University of Genova, Genova, Italy.
Flavio PolitoDepartment of Pharmacy (DIFARMA), University of Salerno, Fisciano, Italy.
Andrea MainettiBiodiversity Service and Scientific Research, Gran Paradiso National Park, Cogne, Italy.
Sana KhedhriLaboratory of Management and Valorization of Forest Resources, National Institute of Research on Rural Engineering, Ariana, Tunisia.
Vincenzo De FeoDepartment of Pharmacy (DIFARMA), University of Salerno, Fisciano, Italy.ORCID https://orcid.org/0000-0002-1070-3207
Laura CornaraDepartment of Earth, Environment and Life Sciences (DISTAV), University of Genova, Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The plant essential oils (EOs) play a fundamental role in the adaptation to different habitats and environmental conditions. To verify the influence of these factors on the EO of Artemisia absinthium L., we conducted a pharmacognostic study on this species, collected during both the vegetative (V) and flowering (F) stages, in two different sites: Cogne (Northern Italy) and Ogliastro Cilento (Southern Italy). At the morphological level, only the shape of the leaf was affected, resulting in smaller and more deeply incised leaves in the Ogliastro samples. Considering the EOs, those from Cogne showed oxygenated monoterpenes as the main class of compounds in both non-flowering (63.88%) and flowering (51.63%) stages, while those from Ogliastro had oxygenated sesquiterpenes (42.17%) as the main class of compounds in the non-flowering stage, and monoterpene hydrocarbons (51.05%) in the flowering one. Moreover, the EOs of plants from the two regions showed qualitative differences; that is, elevated concentrations of myroxide and 3,6-dihydrochamazulene were found in both Cogne samples, while camphor and davanone were found in Ogliastro-V and β-myrcene and β-phellandrene were found in Ogliastro-F. Overall, our data highlighted that both geographical locations and phenological stages influence the phytochemical profile of A. absinthium EOs, suggesting optimal harvesting conditions for maximizing certain bioactive compounds.

Indexed as

ArtemisiaArtemisia absinthiumOils, VolatileFlowersGeographyItalyMonoterpenesPlant LeavesSesquiterpenesMonoterpenesOils, VolatileSesquiterpenesanatomy and micromorphologyAsteraceaeenvironmental conditionsphenological phasephytochemistry

Identifiers

PMID40387081
PMCPMC12533806

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.