ArticlePM & R : the journal of injury, function, and rehabilitation2025
Predicting medical prognosis in patients with glioblastoma during inpatient rehabilitation using bed mobility function.
Article in PM & R : the journal of injury, function, and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Prognostic significance of walking ability at hospital discharge for overall survival in newly diagnosed glioblastoma: a comparison across six peri-treatment assessments.Journal of neuro-oncology · 2026Article
- Predicting medical prognosis in patients with glioblastoma during inpatient rehabilitation using bed mobility function.PM & R : the journal of injury, function, and rehabilitation · 2025Article
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10 authors.
Funding
Abstract
backgroundDetermining appropriate suitability and goals for inpatient rehabilitation of patients with glioblastoma, isocitrate dehydrogenase-wildtype (GBM) requires real-time prognostic information. Functional measures, such as bed mobility, are standardized scores that can be assessed by members of the care team at the bedside and may aid medical prognostication.
objectiveTo analyze the association between bed mobility function during inpatient rehabilitation and 6-month survival post rehabilitation in people with GBM.
designRetrospective cohort study.
settingAcademic inpatient rehabilitation facility (IRF). PATIENTS: One hundred seventy patients with GBM admitted to an IRF over 4.5 years.
interventionsNot applicable.
main outcome measureSurvival 6 months post rehabilitation, regardless of disease progression or events.
resultsUnivariate analyses showed admission (odds ratio [OR] = 1.63, 95% confidence interval [CI] 1.23-2.20; p < .001), discharge (OR = 1.72, 95% CI 1.39-2.16; p <. 001) and gain in bed mobility (OR = 1.64, 95%CI 1.26-2.20; p < .001) were associated with survival. In multivariate analyses adjusting for demographic and clinic variables, admission (OR = 1.91, 95% CI 1.39-2.69; p < .001), discharge (OR = 1.72, 1.38-2.19; p < .001), and gain in bed mobility (OR = 1.62, 95% CI 1.20-2.22; p = .002) were each independently associated with survival. Bed mobility was also independently associated with survival compared to other standard functional independence measures collected in IRF at discharge (OR = 1.88, 95% CI 1.14-3.23; p = .017) and for gain (OR = 1.65, 95% CI 1.10-2.53; p = .018). There was a significant difference in survival between patients with admission bed mobility scores of ≤1 or ≥2 (HR = 3.68, p < .001), discharge scores of ≤1 or ≥2 (HR = 5.72, p<. 001), or a gain of ≤0 or ≥1 (HR = 3.13, p < .001).
conclusionsBed mobility function may serve as a predictor of survival in GBM, suggesting that it could be used during inpatient rehabilitation to help determine functional goals for patients with GBM.
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