Evidence map›Paper›PMID 40386770›Full record

ReviewFrontiers in immunology2025

Case Report: Guillain-Barré syndrome with three episodes and literature review.

Ying Wang, Chunmei Zhao, Rong Chen, Zeli Ma, Nan Tian, Xuan Li, Xianrui Xu, Qiang Liu, Yajun Li, Fenkui She and 2 more

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ying WangClinical Medical College, Ningxia Medical University, Yinchuan, Ningxia, China.
Chunmei ZhaoDepartment of Neurology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China.
Rong ChenDepartment of Neuroelectrophysiology, Cardiovascular and Cerebrovascular Disease Hospital Branch, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China.
Zeli MaClinical Medical College, Ningxia Medical University, Yinchuan, Ningxia, China.
Nan TianClinical Medical College, Ningxia Medical University, Yinchuan, Ningxia, China.
Xuan LiClinical Medical College, Ningxia Medical University, Yinchuan, Ningxia, China.
Xianrui XuDepartment of Neurology, General Hospital of Ningxia Medical University, Ningxia Key Laboratory of Cerebrocranial Diseases, Incubation Base of National Key Laboratory, Yinchuan, Ningxia, China.
Qiang LiuDepartment of Neurology, General Hospital of Ningxia Medical University, Ningxia Key Laboratory of Cerebrocranial Diseases, Incubation Base of National Key Laboratory, Yinchuan, Ningxia, China.
Yajun LiClinical Medical College, Ningxia Medical University, Yinchuan, Ningxia, China.
Fenkui SheClinical Medical College, Ningxia Medical University, Yinchuan, Ningxia, China.
Fenglin MuClinical Medical College, Ningxia Medical University, Yinchuan, Ningxia, China.
Qing ZhangDepartment of Neurology, General Hospital of Ningxia Medical University, Ningxia Key Laboratory of Cerebrocranial Diseases, Incubation Base of National Key Laboratory, Yinchuan, Ningxia, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Guillain-Barré syndrome (GBS) is an autoimmune-mediated peripheral neuropathy that is usually monophasic, but recurrence occurs in 2%-5% of cases, termed recurrent Guillain-Barré syndrome (RGBS). We report the case of a 49-year-old male patient who experienced three episodes of bilateral lower extremity numbness and weakness, each progressing to its nadir within 4 weeks. The first episode was additionally characterized by bilateral upper extremity weakness and dyspnea, while the first two episodes were accompanied by numbness in the fingertips of both hands. Electromyography (EMG) revealed severe axonal damage with concomitant demyelination. Anti-sulfatide IgG antibodies were detected during the third episode. After excluding other demyelinating disorders, a definitive diagnosis of GBS was established, and the symptoms were nearly completely resolved following treatment with intravenous immunoglobulin (IVIG).

Indexed as

Guillain-Barre SyndromeAutoantibodiesElectromyographyHumansImmunoglobulin GImmunoglobulins, IntravenousMaleMiddle AgedRecurrenceAutoantibodiesImmunoglobulin GImmunoglobulins, Intravenousautoimmune diseasescase reportGuillain-Barré syndromeperipheral neuropathyrecurrent Guillain-Barré syndrome

Identifiers

PMID40386770
PMCPMC12081461

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.