Evidence map›Paper›PMID 40386749›Full record

ArticleHCA healthcare journal of medicine2025

Guillain-Barré Syndrome Following Moderna Spikevax Messenger RNA COVID-19 Vaccine: A Case Analysis.

Jamie Lee Aldakkour, Alvin Boyd Newman-Caro, Usama Bardan, Hector Gonzalez-Montalvo, Guruswamy Ramamurthy

Abstract readCase Reports
In one paragraph

Article in HCA healthcare journal of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jamie Lee AldakkourHCA Florida Blake Hospital, Bradenton, Florida.
Alvin Boyd Newman-CaroHCA Florida Blake Hospital, Bradenton, Florida.
Usama BardanHCA Florida Blake Hospital, Bradenton, Florida.
Hector Gonzalez-MontalvoHCA Florida Blake Hospital, Bradenton, Florida.
Guruswamy RamamurthyHCA Florida Blake Hospital, Bradenton, Florida.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Guillain-Barré Syndrome (GBS) is an acute autoimmune polyneuropathy. Cases of GBS have been reported following administration of the vaccines for swine influenza, seasonal influenza, hemagglutinin type 1 and neuraminidase type 1, and meningococcal disease. Despite these links, a causal relationship has not been confirmed. Case Presentation: We present a case of a 70-year-old woman who presented with progressive bilateral ascending weakness and numbness and reported receiving the first dose of the Moderna COVID-19 vaccine 2 weeks prior to presentation. Conclusion: At the time of writing, this is the first reported case of GBS following the Moderna Spikevax COVID-19 vaccine. While a temporal link does not confirm causation, vigilance for GBS symptoms in recently vaccinated patients is crucial. Early recognition enables timely treatment, preventing severe complications like respiratory failure. However, the public health benefits of vaccination far outweigh the risks, as it remains the most effective tool in preventing severe disease.

Indexed as

COVID-19COVID-19 vaccinesGuillain-Barre syndromeSARS-CoV-2vaccination

Identifiers

PMID40386749
PMCPMC12080866

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.