Evidence map›Paper›PMID 40386719›Full record

ArticleTranslational lung cancer research2025

Tracheobronchial resection and reconstruction: to wrap or not to wrap the anastomosis?

Chudong Wang, Zihao Liu, Rui Wang, Biao Hu, Binbin Xiang, Zijian Li, Jianxing He, Shuben Li

Abstract read
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Article in Translational lung cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Chudong Wang *Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, China.
Zihao Liu *Department of Anesthesiology, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Rui Wang *Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, China.
Biao HuGuangzhou Medical University, Guangzhou, China.
Binbin XiangGuangzhou Medical University, Guangzhou, China.
Zijian LiDepartment of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, China.
Jianxing HeDepartment of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, China.
Shuben LiDepartment of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Two opinions in tracheobronchial resection and reconstruction regarding the management of airway anastomosis remain controversial: whether to wrap the anastomosis with surrounding tissue or leave the anastomosis without additional embedding. This study aims to explore the relationship between the choice of anastomotic wrapping and anastomotic complications in tracheobronchial surgery. Methods: Patients who underwent tracheobronchial surgery between January 2019 and December 2021 were retrospectively analyzed. A total of 95 patients were enrolled, and their age and comorbidities were quantified using the age-adjusted Charlson comorbidity index. Based on the length of resection and neoadjuvant therapy, the cases were categorized into the complex surgery group and the standard surgery group. Each group was further divided into wrapped and non-wrapped subgroups. Results: The complex surgery group included 42 patients (wrapped subgroup: 32, non-wrapped subgroup: 10), and the standard surgery group comprised 53 patients (wrapped subgroup: 32, non-wrapped subgroup: 21). In the complex surgery group, the wrapped subgroup exhibited a significantly lower short-term postoperative anastomotic complication rate compared to the non-wrapped subgroup (P=0.004). This included lower rates of anastomotic mild necrosis or stenosis (18.8% Conclusions: The wrapping procedure demonstrated a relatively positive effect in minimizing the risk of short-term anastomotic complications in complex tracheobronchial surgery without impacting long-term anastomotic complications. However, it did not play a significant role in standard tracheobronchial surgery.

Indexed as

anastomosis managementanastomotic wrappingTracheobronchial resection and reconstruction

Identifiers

PMID40386719
PMCPMC12082206

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.