ArticleJournal of medical biochemistry2025
Pituitary cells in man during aging: An immunohistological and morphometric study.
Article in Journal of medical biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Sexual Dimorphism and Aging Effects on Pituitary Gonadotroph Structure and Secretion in Dromedary Camels: Immunohistochemical and Ultrastructural Insights.Veterinary sciences · 2026Article
- Review
- Endocrine effect of ghrelin on histological, hormonal and morphometric parameters of the pituitary gland and the possibility of its clinical application.Journal of medical biochemistry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Aging is a multifactorial process, which inevitably leads to numerous changes in the life of each individual. As the lifespan of people around the world has increased, scientists began to study the mechanisms that would enable high-quality and safe aging. In this review, the focus is on showing the effect of aging on the characteristics of pituitary cells. Methods: In order to write this review, we undertook an electronic literature search through the PubMed and Google Scholar databases using the terms aging, histological, ultrastructure of pituitary cells, also using the "related articles" option. We also analyzed authored and co-authored articles, which were necessary for this type of publication. Results: This review article describes the immuno-histological, ultrastructural and morphometric characteristics of adrenocorticotropic (ACTH), somatotropic (GH), gonadotropic (LH) and folliculostellate (FS) pituitary cells during aging, in young (about 47 years) and old (over 70 years) human cadavers. Conclusions: The described immunohistological and morphometric characteristics of pituitary cells in this review showed that the volume density of ACTH, GH and LH cells was statistically increased (p<0.05) in old cadavers, which indicates an attempt by these cells to bring the pituitary gland to a relatively balanced state.
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Registered trials
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