Evidence map›Paper›PMID 40386423›Full record

ArticleResearch square2025

Identifying individuals at clinical high risk for psychosis using a battery of tasks sensitive to symptom mechanisms.

Trevor Williams, Jim Gold, James Waltz, Jason Schiffman, Lauren Ellman, Gregory P Strauss, Elaine Walker, Scott W Woods, Al Powers, Joshua Kenney and 6 more

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Trevor WilliamsKent State University.ORCID 0000-0003-2202-7020
Jim GoldMPRC.
James WaltzMaryland Psychiatric Research Center.ORCID 0000-0002-9236-3719
Jason Schiffman
Lauren Ellman
Gregory P StraussUniversity of Georiga.
Elaine WalkerEmory University.ORCID 0000-0002-9798-8101
Scott W WoodsYale University School of Medicine.ORCID 0000-0002-3103-5228
Al PowersYale University School of Medicine.ORCID 0000-0003-3057-5043
Joshua Kenney
Minerva Pappu
Philip CorlettYale University.ORCID 0000-0002-5368-1992
Tanya TranUniversity of Rochester Medical Center.ORCID 0000-0002-6303-8394
Steven SilversteinUniversity of Rochester Medical Center.
Richard Zinbarg
Vijay MittalNorthwestern University.ORCID 0000-0001-9017-5119

Funding

5/5 CAPER: Computerized Assessment of Psychosis RiskR01MH120089 · NIMH · YALE UNIVERSITY · PI CORLETT, PHILIP, WOODS, SCOTT W · 2020 to 2024
$3.1M
1/5 CAPER: Computerized Assessment of ProdromE RiskR01MH120090 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI GOLD, JAMES M. · 2020 to 2024
$2.9M
4/5 CAPER: Computerized assessment of psychosis riskR01MH120092 · NIMH · UNIVERSITY OF GEORGIA · PI STRAUSS, GREGORY P · 2020 to 2024
$2.0M
CAPER: Computerized Assessment of Psychosis Risk SupplementR01MH120091 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ELLMAN, LAUREN M · 2020 to 2024
$1.6M
Paranoia and Bias in Social Belief Updating in Clinical High Risk for PsychosisF32MH133302 · NIMH · NORTHWESTERN UNIVERSITY · PI WILLIAMS, TREVOR FORD · 2023 to 2023
$69k
NIMH NIH HHS F32 MH133302NIMH NIH HHS R01 MH120089NIMH NIH HHS R01 MH120090NIMH NIH HHS R01 MH120091NIMH NIH HHS R01 MH120092
6 · The paper itself

Abstract

The clinical high risk for psychosis (CHR-P) population is important for understanding disease progression and treatment; however, standard approaches to identifying CHR-P individuals are expensive and labor-intensive. Focusing on neurocognitive mechanisms that underlie individual psychosis symptoms (positive, negative, and disorganization) may improve screening and identification. The present study examines whether a behavioral task battery that assays symptom mechanisms can identify CHR-P individuals and predict risk severity. Participants (

Identifiers

PMID40386423
PMCPMC12083675

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.