Evidence map›Paper›PMID 40386391›Full record

ArticleResearch square2025

Clinical Significance of Marital Status and Changes in Status Extracted from Unstructured Clinical Notes Using Ensembles of Off-the-Shelf Extraction Models.

Dmitry A Scherbakov, Paul M Heider, Jihad S Obeid, Alexander V Alekseyenko, Leslie A Lenert

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dmitry A ScherbakovMedical University of South Carolina, Charleston, South Carolina, USA.ORCID 0009-0005-7274-0934
Paul M HeiderMedical University of South Carolina, Charleston, South Carolina, USA.ORCID 0000-0002-1589-4567
Jihad S ObeidMedical University of South Carolina, Charleston, South Carolina, USA.
Alexander V AlekseyenkoMedical University of South Carolina, Charleston, South Carolina, USA.
Leslie A LenertMedical University of South Carolina, Charleston, South Carolina, USA.

Funding

South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
NCATS NIH HHS UL1 TR001450
6 · The paper itself

Abstract

Marital status and its dynamics significantly influence health outcomes. This study aims to demonstrate clinical utility of marital status and improve its extraction from electronic health records (EHR) by developing ensembles capable of using structured and unstructured EHR data. Four ensembles based on different voting rules (unanimous vote, majority vote, precision-based vote, and vote based on random forest) were assembled using structured marital status data, off-the-shelf CNN, and hybrid models, capable of detecting marital status from clinical notes, followed by BERT-based fine-tuning to increase recall. Associations of marital status and its changes with depression, substance abuse, and other health outcomes derived from MIMIC-III were reported using frequency statistics. Patients experiencing any marital status change (n=139, including getting married n=40), compared to patients with no change in status (n=2500) of similar age (M=57 years), had higher incidences of depression, but also higher recovery rates, suggesting dual health impacts of marital dynamics.

Indexed as

depressionelectronic health recordsmarital statusnatural language processingSocial determinants of healthsubstance abuse

Identifiers

PMID40386391
PMCPMC12083653

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.