Evidence map›Paper›PMID 40386210›Full record

ArticleFrontiers in nutrition2025

Association between relative fat mass and colorectal cancer: a cross-sectional study.

Yaping Wang, Shilong Song, Lu Zhang, Jingjing Zhang

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yaping WangDepartment of Medical Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Shilong SongDepartment of Radiation Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Lu ZhangDepartment of Medical Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Jingjing ZhangDepartment of Medical Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: We aimed to investigate the potential association between relative fat mass (RFM) and colorectal cancer (CRC). Design and methods: Data from the National Health and Nutrition Examination Survey (NHANES) spanning 1999 to 2020 were analyzed. Associations between RFM and CRC were analyzed using multiple logistic regression. Smoothed curve fitting was performed to conduct the association by sex. The stability of associations was assessed using subgroup analyses and interaction tests. Results: Overall, 52,281 participants over the age of 20 years were enrolled. The fully adjusted model observed a positive association between RFM and CRC, with one-unit increases in RFM linked to a 3% greater prevalence of CRC (OR = 1.03, 95%CI: 1.01, 1.06). A linear positive association was identified between RFM and CRC in male subjects, while a non-linear relationship was observed in females, with an inflection point at 42. Subgroup analysis revealed that age significantly modified the relationship between RFM and CRC ( Conclusion: RFM is strongly associated with CRC prevalence in US adults. Further large-scale prospective investigations are warranted to for verification.

Indexed as

colorectal cancercross-sectionalNHANESobesityrelative fat mass

Identifiers

PMID40386210
PMCPMC12081260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.